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Review
. 2020 Sep;68(9):1750-1763.
doi: 10.4103/ijo.IJO_564_20.

Interleukins and cytokine biomarkers in uveitis

S Balamurugan  1 , Dipankar Das  2 , Murat Hasanreisoglu  3 , Brian C Toy  4 , Mashal Akhter  5 , V K Anuradha  6 , Eliza Anthony  7 , Bharat Gurnani  8 , Kirandeep Kaur  8
Affiliations
Review

Interleukins and cytokine biomarkers in uveitis

S Balamurugan et al. Indian J Ophthalmol. 2020 Sep.

Abstract

Interleukins and cytokines are involved in the pathogenesis of uveitis of heterogeneous origin. Understanding the basics of the ocular immune privilege is a fulcrum to discern their specific role in diverse uveitis to potentially translate as therapeutic targets. This review attempts to cover these elements in uveitis of infectious, noninfectious and masquerade origin. Insights of the molecular targets in novel therapy along with the vision of future research are intriguing.

Keywords: Biologicals; chemokines; interleukins; masquerades.

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Conflict of interest statement

None

Figures

Figure 1
Figure 1
Chemical and molecular mechanisms of anterior chamber associated immune deviation (ACAID)
Figure 2
Figure 2
(a) MCH 2 and helper T cells interaction mechanism (b) MHC 1 and cytotoxic cells interaction mechanism
Figure 3
Figure 3
Dendritic cell and T cell interaction mechanism
See this image and copyright information in PMC

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