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. 1988;75(1):119-23.

[Metastatic neuroblastoma: consolidation treatment with 2 courses of high-dose chemotherapy followed by a bone marrow autograft]

[Article in French]
O Hartmann  1 , E Benhamou, F Beaujean, C Kalifa, O Lejars, C Patte, C Behard, F Flamant, A Thyss, A Deville, et al.
Affiliations
  • PMID: 3282574

[Metastatic neuroblastoma: consolidation treatment with 2 courses of high-dose chemotherapy followed by a bone marrow autograft]

[Article in French]
O Hartmann et al. Bull Cancer. 1988.

Abstract

Among 62 children over 1 year of age at diagnosis who were treated for stage IV neuroblastoma, 33 entered remission after conventional therapy. They received high-dose chemotherapy and in vitro purged bone marrow transplantation as consolidation therapy. Fifteen patients received one course and 18 two courses. At present, 16/33 grafted patients are alive in CR with a median follow-up of 28 months. Toxicity of this regimen was tolerable. Under this treatment, actuarial disease free survival is improved compared with that observed under conventional therapy.

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