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. 2020 Dec:144:e227-e236.
doi: 10.1016/j.wneu.2020.08.101. Epub 2020 Aug 20.

Microsurgery for Spetzler-Martin Grade I-III Arteriovenous Malformations: Analysis of Surgical Results and Correlation of Lawton-Young Supplementary Grade and Supplemented Spetzler-Martin Score with Functional Outcome

Narayanam Anantha Sai Kiran  1 , Kanneganti Vidyasagar  2 , Vivek Raj  1 , Laxminadh Sivaraju  1 , Rakshith Srinivasa  1 , Dilip Mohan  1 , Alangar S Hegde  1
Affiliations

Microsurgery for Spetzler-Martin Grade I-III Arteriovenous Malformations: Analysis of Surgical Results and Correlation of Lawton-Young Supplementary Grade and Supplemented Spetzler-Martin Score with Functional Outcome

Narayanam Anantha Sai Kiran et al. World Neurosurg. 2020 Dec.

Abstract

Objective: To analyze the results of microsurgery for Spetzler-Martin (SM) grade I-III AVMs and evaluate the correlation of the Lawton-Young (LY) supplementary grade, supplemented Spetzler-Martin (SM-Supp/combined) score with the functional outcome.

Methods: A total of 42 patients with SM grade I-III AVMs who had undergone surgery at our institute during a 3-year period (June 2013 to May 2016) were included in the present study.

Results: All 42 patients had undergone primary surgery without previous embolization. Three patients (7.1%) had died due to surgical site hematoma in the postoperative period. One patient was lost to follow-up. The mean follow-up period for the remaining patients was 27 ± 14 months (range, 12-62 months). At the final follow-up examination of ≥12 months (FFU), 92.7% of the patients had a good outcome (modified Rankin scale [mRS] score ≤1), with an improved or unchanged mRS score in 87.8%. An AVM size >3 cm, diffuse AVM, SM grade III, and SM-Supp score >5 were associated with worsened mRS score at discharge and FFU. Higher LY grade (IV and V), eloquent AVM location, deep venous drainage, age >40 years, and unruptured presentation were not associated with worsened mRS score at both discharge and FFU. Of the 20 ARUBA-eligible patients, 19 (95%) had good outcomes. Postoperative angiograms for 39 patients revealed complete excision of the AVM in 37 (94.9%) and a residual AVM in 2 (5.1%).

Conclusions: High cure rates and excellent clinical outcomes can be expected with microsurgery for most patients with SM grade I-III AVMs. An AVM size >3 cm, diffuse AVM nidus, SM grade III, and SM-Supp score >5 are associated with postoperative worsening of functional scores in patients with SM grade I-III AVMs.

Keywords: ARUBA trial; Cerebral arteriovenous malformations; Large AVMs; Microsurgery for AVMs; Spetzler-Martin grade; Supplemented Spetzler-Martin score; Young-Lawton supplementary grade.

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