ANERGY TO SYNERGY-THE ENERGY FUELING THE RXCOVEA FRAMEWORK

doi:10.1615/intjmultcompeng.2020035097

. 2020;18(3):329-333.

doi: 10.1615/intjmultcompeng.2020035097.

ANERGY TO SYNERGY-THE ENERGY FUELING THE RXCOVEA FRAMEWORK

Evelyne Bischof^{1

2}, Jantine A C Broek³, Charles R Cantor^{4

5}, Ashley J Duits⁶, Alfredo Ferro⁷, Hillary W Gao⁸, Zilong Li⁹, Stella Luna de Maria¹⁰, Naomi I Maria^{6

11}, Bud Mishra¹², Kimberly I Mishra⁸, Lex van der Ploeg^{12

13}, Larry Rudolph¹⁴, Tamar Schlick⁹; RxCOVEA Framework

Affiliations

¹ Insilico Medicine, 307A, E1, Hong Kong Science and Technology Park, Hong Kong, People's Republic of China.
² Department of Advanced Biomedical Sciences, Federico II University of Naples, Via Pansini, 5, 80131, Naples, Italy.
³ Department of Electrical Engineering and Computer Science, ULiége, Liége, Belgium.
⁴ Department of Biomedical Engineering, Boston University, Boston, Massachusetts, USA.
⁵ Retrotope, Inc., Los Altos, California, USA.
⁶ Red Cross Blood Bank Foundation Curaçao, Willemstad, Curaçao.
⁷ Department of Clinical and Experimental Medicine, Catania University, Italy.
⁸ Department of Physics, New York University, New York, New York, USA.
⁹ Department of Chemistry and Courant Institute of Mathematical Sciences, New York University, New York, New York, USA.
¹⁰ Pentaquark Consulting, Madrid, Spain.
¹¹ Institute of Molecular Medicine, The Feinstein Institutes for Medical Research, Northwell Health, Manhasset, New York, USA.
¹² Department of Computer Science, Mathematics, Engineering and Cell Biology, Courant Inst, Tandon and School of Medicine, New York University, New York, New York, USA.
¹³ Yao-The Bard LLC, Plymouth, Massachusetts, USA.
¹⁴ Department of Computer Science, MIT, Boston, Massachusetts, USA.

PMID: 32831809
PMCID: PMC7440281
DOI: 10.1615/intjmultcompeng.2020035097

ANERGY TO SYNERGY-THE ENERGY FUELING THE RXCOVEA FRAMEWORK

Evelyne Bischof et al. Int J Multiscale Comput Eng. 2020.

. 2020;18(3):329-333.

doi: 10.1615/intjmultcompeng.2020035097.

Authors

Affiliations

¹ Insilico Medicine, 307A, E1, Hong Kong Science and Technology Park, Hong Kong, People's Republic of China.
² Department of Advanced Biomedical Sciences, Federico II University of Naples, Via Pansini, 5, 80131, Naples, Italy.
³ Department of Electrical Engineering and Computer Science, ULiége, Liége, Belgium.
⁴ Department of Biomedical Engineering, Boston University, Boston, Massachusetts, USA.
⁵ Retrotope, Inc., Los Altos, California, USA.
⁶ Red Cross Blood Bank Foundation Curaçao, Willemstad, Curaçao.
⁷ Department of Clinical and Experimental Medicine, Catania University, Italy.
⁸ Department of Physics, New York University, New York, New York, USA.
⁹ Department of Chemistry and Courant Institute of Mathematical Sciences, New York University, New York, New York, USA.
¹⁰ Pentaquark Consulting, Madrid, Spain.
¹¹ Institute of Molecular Medicine, The Feinstein Institutes for Medical Research, Northwell Health, Manhasset, New York, USA.
¹² Department of Computer Science, Mathematics, Engineering and Cell Biology, Courant Inst, Tandon and School of Medicine, New York University, New York, New York, USA.
¹³ Yao-The Bard LLC, Plymouth, Massachusetts, USA.
¹⁴ Department of Computer Science, MIT, Boston, Massachusetts, USA.

PMID: 32831809
PMCID: PMC7440281
DOI: 10.1615/intjmultcompeng.2020035097

Abstract

We write to introduce our novel group formed to confront some of the issues raised by the COVID-19 pandemic. Information about the group, which we named "cure COVid for Ever and for All" (RxCOVEA), its dynamic membership (changing regularly), and some of its activities-described in more technical detail for expert perusal and commentary-are available upon request.

Keywords: COVID-19 research; bioinformatics; immunology; systems biology.

PubMed Disclaimer

Conflict of interest statement

CONFLICT OF INTEREST E.B. is an executive member of Women’s Brain Project, Switzerland.

Figures

**FIG. 1:**
The “cure COVid for Ever and for All” (RxCOVEA) Framework: A Global Network. Pan-national members of RxCOVEA superimposed on the pandemic viral genomic tracing map of COVID-19 spread (Gisaid.org). The serious health and economic consequences of the interconnected world in spreading the infection are contrasted by the rigorous science and technology projects, self-assembling spontaneously and equally rapidly around the globe (representative images shown of RxCOVEA member locality).

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Maria NI, Rapicavoli RV, Alaimo S, Bischof E, Stasuzzo A, Broek JAC, Pulvirenti A, Mishra B, Duits AJ, Ferro A; RxCOVEA Framework. Maria NI, et al. Heliyon. 2023 Mar;9(3):e14115. doi: 10.1016/j.heliyon.2023.e14115. Epub 2023 Mar 6. Heliyon. 2023. PMID: 36911878 Free PMC article.

References

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[1] De Clercq E and Li G, Approved Antiviral Drugs over the past 50 Years, Clin. Microbiol. Rev, vol. 29, no. 3, pp. 695–747, 2016. - PMC - PubMed

[2] De Clercq E and Li G, Approved Antiviral Drugs over the past 50 Years, Clin. Microbiol. Rev, vol. 29, no. 3, pp. 695–747, 2016. - PMC - PubMed

[3] Du SQ and Yuan W, Mathematical Modeling of Interaction between Innate and Adaptive Immune Responses in COVID-19 and Implications for Viral Pathogenesis, J. Med. Virol, 2020. (ahead of print). DOI: 10.1002/jmv.25866 - DOI - PMC - PubMed

[4] Du SQ and Yuan W, Mathematical Modeling of Interaction between Innate and Adaptive Immune Responses in COVID-19 and Implications for Viral Pathogenesis, J. Med. Virol, 2020. (ahead of print). DOI: 10.1002/jmv.25866 - DOI - PMC - PubMed

[5] Gandhi M, Yokoe DS, and Havlir DV, Asymptomatic Transmission, the Achilles’ Heel of Current Strategies to Control COVID-19, N. Engl. J. Med, 2020. (ahead of print). DOI: 10.1056/nejme2009758 - DOI - PMC - PubMed

[6] Gandhi M, Yokoe DS, and Havlir DV, Asymptomatic Transmission, the Achilles’ Heel of Current Strategies to Control COVID-19, N. Engl. J. Med, 2020. (ahead of print). DOI: 10.1056/nejme2009758 - DOI - PMC - PubMed

[7] He X, Lau EH, Wu P, Deng X, Wang J, Hao X, Lau YC, Wong JY, Guan Y, Tan X, and Mo X, Temporal Dynamics in Viral Shedding and Transmissibility of COVID-19, Nat. Med, vol. 26, no. 5, pp. 672–675, 2020. - PubMed

[8] He X, Lau EH, Wu P, Deng X, Wang J, Hao X, Lau YC, Wong JY, Guan Y, Tan X, and Mo X, Temporal Dynamics in Viral Shedding and Transmissibility of COVID-19, Nat. Med, vol. 26, no. 5, pp. 672–675, 2020. - PubMed

[9] Jewell NP, Lewnard JA, and Jewell BL, Caution Warranted: Using the Institute for Health Metrics and Evaluation Model for Predicting the Course of the COVID-19 Pandemic, Ann. Intern. Med, 2020. (ahead of print). DOI: 10.7326/m20-1565 - DOI - PMC - PubMed

[10] Jewell NP, Lewnard JA, and Jewell BL, Caution Warranted: Using the Institute for Health Metrics and Evaluation Model for Predicting the Course of the COVID-19 Pandemic, Ann. Intern. Med, 2020. (ahead of print). DOI: 10.7326/m20-1565 - DOI - PMC - PubMed

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ANERGY TO SYNERGY-THE ENERGY FUELING THE RXCOVEA FRAMEWORK

Affiliations

ANERGY TO SYNERGY-THE ENERGY FUELING THE RXCOVEA FRAMEWORK

Authors

Affiliations

Abstract

Conflict of interest statement

Figures

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References

Grants and funding

LinkOut - more resources

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