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Editorial
. 2021 Jun;66(6):1772-1774.
doi: 10.1007/s10620-020-06565-z.

Vedolizumab Dose Escalation: In for a Penny, in for a Pound?

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Editorial

Vedolizumab Dose Escalation: In for a Penny, in for a Pound?

Robin J Dart et al. Dig Dis Sci. 2021 Jun.
No abstract available

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References

    1. Perry C, Fischer K, Elmoursi A, et al. Vedolizumab dose escalation improves therapeutic response in a subset of patients with ulcerative colitis. Dig Dis Sci. (Epub ahead of print). https://doi.org/10.1007/s10620-020-06486-x .
    1. Peyrin-Biroulet L, Danese S, Argollo M, et al. Loss of response to vedolizumab and ability of dose intensification to restore response in patients with Crohn’s disease or ulcerative colitis: a systematic review and meta-analysis. Clin Gastroenterol Hepatol. 2019;17:838–846. - DOI
    1. Samaan MA, Birdi S, Morales MS, et al. Effectiveness of vedolizumab dose intensification to achieve inflammatory bowel disease control in cases of suboptimal response. Frontline Gastroenterol. 2020;11:188–193. - DOI
    1. Ungar B, Kopylov U, Yavzori M, et al. Association of vedolizumab level, anti-drug antibodies, and alpha4beta7 occupancy with response in patients with inflammatory bowel diseases. Clin Gastroenterol Hepatol. 2018;16:697.e7–705.e7. - DOI
    1. Rath T, Billmeier U, Ferrazzi F, et al. Effects of anti-integrin treatment with vedolizumab on immune pathways and cytokines in inflammatory bowel diseases. Front Immunol. 2018;9:1700. - DOI

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