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Review
. 2020 Jul-Sep;47(3):96-105.
doi: 10.1016/j.gine.2020.06.004. Epub 2020 Jun 19.

[SARS-CoV-2 pandemic and assisted reproduction]

[Article in Spanish]
A Borrás  1 , M Guimerà  1 , Y Barral  1 , I Agustí  1 , M D Manau Trullàs  1
Affiliations
Review

[SARS-CoV-2 pandemic and assisted reproduction]

[Article in Spanish]
A Borrás et al. Clin Invest Ginecol Obstet. 2020 Jul-Sep.

Abstract
in English, Spanish

The pandemic caused by the new SARS-CoV-2 virus has led to a process of adaptation to the new situation by society as a whole and, therefore, by assisted reproduction centres. After the acute phase of the health crisis, when activity was drastically reduced, cycles have resumed, guided by the recommendations of scientific societies.In this article, a review is presented of all the published information regarding the virus and the reproductive system, pointing out the presence of angiotensin-converting enzyme 2 (ACE2) in the female and male reproductive system, at the testicular, ovarian, endometrial and embryonic levels. In addition, a comparative analysis is carried out between the recommendations of the scientific societies regarding the screening of infection, performance standards, and general laboratory measurements.

La pandemia por el nuevo virus SARS-CoV-2 ha provocado un proceso de adaptación a la nueva situación por parte de toda de la sociedad y, con ello, los centros de reproducción asistida. Tras la fase aguda de la crisis sanitaria, en la que se redujo de forma drástica la actividad, se han reanudado los ciclos, guiados por las recomendaciones de las sociedades científicas.

En este artículo revisamos toda la información publicada respecto al virus y el sistema reproductivo, señalando la presencia de enzima convertidora de angiotensina tipo ii(angiotensin-converting enzyme 2, ACE2) en el sistema reproductivo femenino y masculino, a nivel testicular, ovárico, endometrial y a nivel embrionario. Además, realizamos un análisis comparativo entre las recomendaciones de las sociedades científicas en cuanto al cribado de la infección, las normas de funcionamiento y las medidas generales de laboratorio.

Keywords: Embryos; Human reproductive system; Ovary; SARS-CoV-2; Semen; Testes; Uterus.

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Figures

Figura 1
Figura 1
Localización y probable función de ACE2 en el sistema reproductor femenino.
Figura 2
Figura 2
Localización y probable función de ACE2 en el sistema reproductor masculino.
See this image and copyright information in PMC

References

    1. Cucinotta D., Vanelli M. WHO Declares COVID-19 a Pandemic. Acta Biomed. 2020;91:157–160. doi: 10.23750/abm.v91i1.9397. - DOI - PMC - PubMed
    1. Monteleone P.A., Nakano M., Lazar V., Gomes A.P., de Martin H., Bonetti T.C. A review of initial data on pregnancy during the COVID-19 out-break: Implications for assisted reproductive treatments. JBRA Reprod Assist. 2020;24:219–225. doi: 10.5935/1518-0557.20200030. - DOI - PMC - PubMed
    1. International Federation of Fertility societies. IFFS COVID-19 Task Force Statements. 2020 Disponible en: https://www.iffsreproduction.org/page/COVIDStatements.
    1. European Society of Human Reproduction and Embryology. ESHRE News and Statements. 2020 Disponible en: https://www.eshre.eu/Press-Room/ESHRE-News; 2020.
    1. Sociedad Española de Fertilidad. Comunicado SEF 15 marzo 2020. 2020 Disponible en: https://www.sefertilidad.net/docs/noticias/notaCoronavirus.pdf.

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