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Review
. 2020;28(1):169-185.
doi: 10.1007/s10499-019-00451-w. Epub 2019 Aug 10.

Diagnosis and potential treatments for acute hepatopancreatic necrosis disease (AHPND): a review

Harvey M Santos  1 , Ching-Yi Tsai  1 , Kenth Roger A Maquiling  2 , Lemmuel L Tayo  2 , Abdul R Mariatulqabtiah  3 , Chi-Wen Lee  4 , Kuo Pin Chuang  1   5   6
Affiliations
Review

Diagnosis and potential treatments for acute hepatopancreatic necrosis disease (AHPND): a review

Harvey M Santos et al. Aquac Int. 2020.

Abstract

Acute hepatopancreatic necrosis disease (AHPND) or formerly known as early mortality syndrome (EMS) is an emerging disease that has caused significant economic losses to the aquaculture industry. The primary causative agent of AHPND is Vibrio parahaemolyticus, a Gram-negative rod-shaped bacterium that has gained plasmids encoding the fatal binary toxins Pir A/Pir B that cause rapid death of the infected shrimp. In this review, the current research studies and information about AHPND in shrimps have been presented. Molecular diagnostic tools and potential treatments regarding AHPND were also included. This review also includes relevant findings which may serve as guidelines that can help for further investigation and studies on AHPND or other shrimp diseases.

Keywords: Acute hepatopancreatic necrosis disease (AHPND); Diagnosis; Pir A; Pir B; Treatment.

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Conflict of interest statement

Conflict of interestThe authors declare that they have no conflicts of interest.

Figures

Fig. 1
Fig. 1
Process flow diagram of detecting and handling of AHPND-infected samples
See this image and copyright information in PMC

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