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Case Reports
. 2020 Nov:33:101338.
doi: 10.1016/j.eucr.2020.101338. Epub 2020 Jul 7.

Low back pain revealing a primary small cell neuroendocrine carcinoma of the upper urinary tract: A case report and review of the literature

Craig Aurtz Tombet  1 , Mohammed Aynaou  1 , Tarik Mhanna  1 , Amine El Houmaidi  1 , Miry Achraf  2 , Ali Barki  1
Affiliations
Case Reports

Low back pain revealing a primary small cell neuroendocrine carcinoma of the upper urinary tract: A case report and review of the literature

Craig Aurtz Tombet et al. Urol Case Rep. 2020 Nov.

Abstract

Small cell carcinoma of the upper urinary tract is very rare. Their aggressiveness and their poor prognosis make it grave. We report the management of a patient who consulted in the emergency room for low back pain and to whom the radiological and endoscopic assessments found a tumor of the upper urinary tract with lung, liver, bone and adrenal damage. Anatomopathological study of biopsies obtained by flexible ureteroscopy and percutaneous liver biopsy confirmed the diagnosis and the metastatic nature of secondary lesions.

Keywords: Extrapulmonary small cell carcinoma; Small cell neuroendocrine carcinoma; Upper urinary tract.

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Conflict of interest statement

The authors do not declare any conflict of interest.

Figures

Fig. 1
Fig. 1
CT image showing a upper calyx tissue process of right upper urinary tract; the lung, liver and bone damage.
Fig. 2
Fig. 2
Endoscopic image showing the tumor in the upper calyx.
Fig. 3
Fig. 3
Microphotography showing a proliferation made of sheets of small blue cells. The nucleocytoplasmic is high with numerous mitotic figures. (HE, 400X). (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
See this image and copyright information in PMC

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