Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2020 Jul 15;2(9):1267-1270.
doi: 10.1016/j.jaccas.2020.05.082. Epub 2020 Jun 18.

Cardiac Dysfunction and Shock in Pediatric Patients With COVID-19

Krittika Joshi  1 , Daniel Kaplan  2 , Adnan Bakar  2 , John F Jennings  2 , Denise A Hayes  1 , Siddharth Mahajan  1 , Nilanjana Misra  1 , Elizabeth Mitchell  1 , Todd M Sweberg  2 , Matthew D Taylor  2   3 , Christine A Capone  2   3
Affiliations
Case Reports

Cardiac Dysfunction and Shock in Pediatric Patients With COVID-19

Krittika Joshi et al. JACC Case Rep. .

Abstract

Coronavirus disease-2019 (COVID-19) has been reported to cause significant morbidity in adults, with reportedly a lesser impact on children. Cardiac dysfunction has only been described in adults thus far. We describe 3 cases of previously healthy children presenting with shock and COVID-19-related cardiac inflammation. (Level of Difficulty: Intermediate.).

Keywords: AKI, acute kidney injury; COVID-19; COVID-19, coronavirus disease-2019; ED, emergency department; FS, fractional shortening; IVIG, intravenous immunoglobulin; LVEF, left ventricular ejection fraction; PCR, polymerase chain reaction; PICU, pediatric intensive care unit; TTE, transthoracic echocardiogram; VIS, vasoactive ionotropic score; cardiac injury; hsTnT, high-sensitivity troponin T; myocarditis; pediatric; shock.

PubMed Disclaimer

Comment in

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Lu X., Zhang L., Du H. SARS-CoV-2 infection in children. N Engl J Med. 2020;382:1663–1665. - PMC - PubMed
    1. Pediatric Intensive Care Society PICS Statement regarding novel presentation of multi-system inflammatory disease. https://picsociety.uk/news/pics-statement-regarding-novel-presentation-o... Available at:
    1. Akhmerov A., Marban E. COVID-19 and the heart. Circ Res. 2020;126:1443–1455. - PMC - PubMed
    1. Li H., Liu L., Zhang D. SARS-CoV-2 and viral sepsis: observations and hypotheses. Lancet. 2020;395:1517–1520. - PMC - PubMed
    1. Tavazzi G., Pellegrini C., Maurelli M. Myocardial localization of coronavirus in COVID-19 cardiogenic shock: COVID-19 does not spare the heart. Eur J Heart Fail. 2020;22:911–915. - PMC - PubMed

Publication types