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. 2020;32(3):1875-1877.
doi: 10.1007/s10811-020-02143-y. Epub 2020 Jun 1.

The COVID 19 novel coronavirus pandemic 2020: seaweeds to the rescue? Why does substantial, supporting research about the antiviral properties of seaweed polysaccharides seem to go unrecognized by the pharmaceutical community in these desperate times?

Leonel Pereira  1 , Alan T Critchley  2
Affiliations

The COVID 19 novel coronavirus pandemic 2020: seaweeds to the rescue? Why does substantial, supporting research about the antiviral properties of seaweed polysaccharides seem to go unrecognized by the pharmaceutical community in these desperate times?

Leonel Pereira et al. J Appl Phycol. 2020.

Abstract

Presently, there is lack of a vaccine that would lead to immunization against the virus COVID-19, but here are some of the characteristics that various seaweeds have and which may provide a glimpse into potential solutions of this global health problem in the near future and possibly forearm us for any future such pandemics. Many species of marine algae contain significant quantities of complex structural sulphated polysaccharides that have been shown to inhibit the replication of enveloped viruses. Other compounds, both of red algae (e.g., the lectin griffithsin and the phycocolloid carrageenan), and other sulphated polysaccharides extracted from green algae (i.e., ulvans) and brown algae (i.e., fucoidans) could be potential antiviral therapeutic agents against SARS-CoV-2.

Keywords: Antiviral properties; COVID-19; Novel coronavirus; Pandemic 2020; Seaweed compounds; Sulphated polysaccharides.

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References

    1. Barre A, Simplicien M, Benoist H, Van Damme EJM, Rouge P. Mannose-specific lectins from marine algae: diverse structural scaffolds associated to common virucidal and anti-cancer properties. Mar Drugs. 2019;17:440. doi: 10.3390/md17080440. - DOI - PMC - PubMed
    1. Barton C, Kouokam JC, Lasnik AB, Foreman O, Cambon A, Brock G, Montefiori DC, Vojdani F, McCormick AA, O'Keefe BR, Palmer KE (2014) Activity of and effect of subcutaneous treatment with the broad-spectrum antiviral lectin griffithsin in two laboratory rodent models. Antimicrob Agents Chemother 58:120–127 - PMC - PubMed
    1. Booker B (2020) Japan declares nationwide state of emergency as coronavirus spreads. NPR (National Public Radio). Available at: https://www.npr.org/sections/coronavirus-live-updates/2020/04/16/8359250... (accessed on Apr 22, 2020)
    1. Canducci F, Debiaggi M, Sampaolo M, Marinozzi MC, Berre S, Terulla C, Gargantini G, Cambieri P, Romero E, Clementi M. Two-year prospective study of single infections and co-infections by respiratory syncytial virus and viruses identified recently in infants with acute respiratory disease. J Med Virol. 2008;80:716–723. doi: 10.1002/jmv.21108. - DOI - PMC - PubMed
    1. Eccles R, Meier C, Jawad M, Weinmullner R, Grassauer A, Prieschl-Grassauer E. Efficacy and safety of an antiviral iota-carrageenan nasal spray: a randomized, double-blind, placebo controlled exploratory study in volunteers with early symptoms of the common cold. Respir Res. 2010;11:108. doi: 10.1186/1465-9921-11-108. - DOI - PMC - PubMed

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