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. 2020 Sep;31(3):316-322.
doi: 10.1007/s13337-020-00614-x. Epub 2020 Aug 6.

Prevalence and associated factors to rotavirus infection in children less than 5 years in Enugu State, Nigeria

C D Ojobor  1   2 , C V Olovo  1 , L O Onah  1   3 , A C Ike  1
Affiliations

Prevalence and associated factors to rotavirus infection in children less than 5 years in Enugu State, Nigeria

C D Ojobor et al. Virusdisease. 2020 Sep.

Abstract

Rotavirus is an important cause of morbidity and mortality in children 5 years and below. An epidemiological study was carried out to determine the prevalence of rotavirus in Enugu state and factors that contribute to the incidence in the state. Stool samples were collected from 179 children from different parts of the state. Rotavirus antigen was detected using enzyme immunoassay kit. A standardized structured questionnaire was used to obtain additional information from the parents/guardian of the children. Chi square was used to analyze the results and significance was determined at 0.05. The results showed 31.5% prevalence of rotavirus among children with acute gastroenteritis (AGE) and 25.7% prevalence in the general population. The prevalence was highest (60.9%) among children 0-12 months and decreased as the age increased. Rotavirus infection was significantly higher in bottle-fed children than in those feed exclusively breast milk. More viruses were detected in O (48.8%) and A (47.6%) blood group children than in children of other blood groups. More rotavirus caused AGE occurred in dry season compared to wet season, with highest incidence of both AGE and rotavirus infection occurring in January. Rotavirus diarrhoea was significantly associated with fever, vomiting and dehydration. The results of this study show that rotavirus continues to be an important cause of diarrhoea in children in this part of Nigeria and emphasize the need to factor in rotavirus and other viral agents in the diagnosis and treatment of diarrhoea in children 5 years and below.

Keywords: Children; Diarrhoea; Enzyme immunoassay (EIA); Prevalence; Rotavirus.

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Conflict of interest statement

Conflict of interestAuthors declare no conflicting interests.

Figures

Fig. 1
Fig. 1
Prevalence of rotavirus infection in different age groups of children with acute gastroenteritis
Fig. 2
Fig. 2
Seasonality of acute gastroenteritis and the rotavirus infections among 146 children suffering from AGE between September 2014 and May 2015
See this image and copyright information in PMC

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