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Review
. 2020;2(8):1109-1119.
doi: 10.1007/s42399-020-00364-3. Epub 2020 Jul 13.

Coronavirus Disease of 2019: a Mimicker of Dengue Infection?

Joshua Henrina  1 , Iwan Cahyo Santosa Putra  1 , Sherly Lawrensia  1   2 , Quinta Febryani Handoyono  1 , Alius Cahyadi  3
Affiliations
Review

Coronavirus Disease of 2019: a Mimicker of Dengue Infection?

Joshua Henrina et al. SN Compr Clin Med. 2020.

Abstract

At the beginning of 2020, the national health system and medical communities are faced with unprecedented public health challenges. A novel strain of coronavirus, later identified as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread globally, marking another pandemic of coronaviruses. This viral disease is responsible for devastating pneumonia, named coronavirus disease of 2019 (COVID-19), and projected to persist until the end of the year. In tropical countries, however, concerns arise regarding the similarities of COVID-19 with other infectious diseases due to the same chief complaint, which is fever. One of the infectious disease of a primary concern is dengue infection, which its peak season is approaching. Others report that there are cases of serological cross-reaction of COVID-19 and dengue infection. In this comprehensive review, we underscore the importance of knowing similar clinical presentations of both diseases and emphasize why excluding COVID-19 in the differentials in the setting of a pandemic is imprudent.

Keywords: COVID-19; DENV; Dengue; Mimicker; SARS-CoV-2.

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Conflict of interest statement

Competing InterestsThe authors declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
SARS-CoV2 and DENV pathomechanisms of clinical manifestations. This flowchart diagram depicts similarities between COVID-19 and DENV clinical manifestations with their respective pathomechanisms
See this image and copyright information in PMC

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