Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2020;2(9):1377-1387.
doi: 10.1007/s42399-020-00417-7. Epub 2020 Jul 20.

Coronavirus Disease 2019 (COVID-19) as a Multi-Systemic Disease and its Impact in Low- and Middle-Income Countries (LMICs)

Affiliations
Review

Coronavirus Disease 2019 (COVID-19) as a Multi-Systemic Disease and its Impact in Low- and Middle-Income Countries (LMICs)

Mazou Ngou Temgoua et al. SN Compr Clin Med. 2020.

Abstract

Currently, the coronavirus disease 2019 (COVID-19) is the priority of the global health agenda. Since the first case was reported in Wuhan, China, this infection has continued to spread and has been considered as a pandemic by the World Health Organization (WHO) within 3 months of its outbreak. Several studies have been done to better understand the pathogenesis and clinical aspects of the disease. It appears that COVID-19 affects almost all body organs due to the direct effect of the virus and its induced widespread inflammatory response. This multi-systemic aspect of the disease has to be inculcated in COVID-19 management by health providers to improve patient outcomes. This strategy could help curb the burden of the disease especially in low- and middle-income countries (LMICs) like most African countries where the pandemic is at an "embryonic" stage.

Keywords: Coronavirus disease 2019; Low- and middle-income countries; Multi-systemic disease; Therapeutical implication.

PubMed Disclaimer

Conflict of interest statement

Conflict of InterestThe authors declare that they have no competing interests.

References

    1. Guo Y-R, Cao Q-D, Hong Z-S, Tan Y-Y, Chen S-D, Jin H-J, et al. The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak - an update on the status. Mil Med Res. 2020;7(1):11. - PMC - PubMed
    1. WHO. Coronavirus disease 2019 (COVID-19) Situation Report – 90. [cited 2020 Apr 19]; Available from: https://www.who.int/docs/default-source/coronaviruse/situation-reports/2...
    1. StatPearls. Treasure Island (FL): StatPearls Publishing; 2020.
    1. Guan W, Ni Z, Hu Y, Liang W, Ou C, He J, et al. Clinical characteristics of coronavirus disease 2019 in China. New England J Med. 2020 Feb 28 [cited 2020 Apr 17]; Available from: h10.1056/NEJMoa2002032 - PMC - PubMed
    1. Bai Y, Yao L, Wei T, Tian F, Jin D-Y, Chen L, Wang M. Presumed asymptomatic carrier transmission of COVID-19. JAMA. 2020;323(14):1406. - PMC - PubMed

LinkOut - more resources