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Review
. 2020;2(9):1430-1435.
doi: 10.1007/s42399-020-00454-2. Epub 2020 Aug 14.

Arrhythmia in COVID-19

Savalan Babapoor-Farrokhran  1 , Roozbeh Tarighati Rasekhi  2 , Deanna Gill  3 , Shaghayegh Babapoor  4 , Aman Amanullah  1   5
Affiliations
Review

Arrhythmia in COVID-19

Savalan Babapoor-Farrokhran et al. SN Compr Clin Med. 2020.

Abstract

The current outbreak of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) also known as coronavirus disease 2019 (COVID-19) has quickly progressed to a global pandemic. There are well-documented cardiac complications of COVID-19 in patients with and without prior cardiovascular disease. The cardiac complications include myocarditis, heart failure, and acute coronary syndrome resulting from coronary artery thrombosis or SARS-CoV-2-related plaque ruptures. There is growing evidence showing that arrhythmias are also one of the major complications. Myocardial inflammation caused by viral infection leads to electrophysiological and structural remodeling as a possible mechanism for arrhythmia. This could also be the mechanism through which SARS-CoV-2 leads to different arrhythmias. In this review article, we discuss arrhythmia manifestations in COVID-19.

Keywords: Arrhythmias; Atrial fibrillation; Coronavirus disease 2019; Middle east respiratory syndrome; QT prolongation; Severe acute respiratory syndrome; Sinus bradycardia; Sinus tachycardia; Torsade de pointes; Ventricular arrhythmias; Ventricular fibrillation; Ventricular tachycardia; Viral infection.

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Conflict of interest statement

Conflict of InterestThe authors declare that they have no conflict of interest.

Figures

Fig. 1
Fig. 1
Arrhythmia manifestations of COVID-19 and possible mechanisms
See this image and copyright information in PMC

References

    1. COVID-19 Map.In: Johns Hopkins Coronavirus Resource Center [Internet]. [cited 9 Apr 2020]. Available: https://coronavirus.jhu.edu/map.html. Accessed 11 June 2020.
    1. Babapoor-Farrokhran S, Gill D, Walker J, Rasekhi RT, Bozorgnia B, Amanullah A. Myocardial injury and COVID-19: possible mechanisms. Life Sci. 2020;253:117723. doi: 10.1016/j.lfs.2020.117723. - DOI - PMC - PubMed
    1. Liu K, Fang Y-Y, Deng Y, Liu W, Wang M-F, Ma J-P, Xiao W, Wang YN, Zhong MH, Li CH, Li GC, Liu HG. Clinical characteristics of novel coronavirus cases in tertiary hospitals in Hubei Province. Chin Med J. 2020;133(9):1025–1031. doi: 10.1097/CM9.0000000000000744. - DOI - PMC - PubMed
    1. Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J, Wang B, Xiang H, Cheng Z, Xiong Y, Zhao Y, Li Y, Wang X, Peng Z. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan. China JAMA. 2020;323:1061. doi: 10.1001/jama.2020.1585. - DOI - PMC - PubMed
    1. Gaaloul I, Riabi S, Harrath R, Evans M, Salem NH, Mlayeh S, Huber S, Aouni M. Sudden unexpected death related to enterovirus myocarditis: histopathology, immunohistochemistry and molecular pathology diagnosis at post-mortem. BMC Infect Dis. 2012;12:212. doi: 10.1186/1471-2334-12-212. - DOI - PMC - PubMed

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