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. 2020 Oct;26(Supp 1):i125-i153.
doi: 10.1136/injuryprev-2019-043531. Epub 2020 Aug 24.

Estimating global injuries morbidity and mortality: methods and data used in the Global Burden of Disease 2017 study

Spencer L James  1 Chris D Castle  1 Zachary V Dingels  1 Jack T Fox  1 Erin B Hamilton  1 Zichen Liu  1 Nicholas L S Roberts  1 Dillon O Sylte  1 Gregory J Bertolacci  1 Matthew Cunningham  1 Nathaniel J Henry  1 Kate E LeGrand  1 Ahmed Abdelalim  2 Ibrahim Abdollahpour  3 Rizwan Suliankatchi Abdulkader  4 Aidin Abedi  5 Kedir Hussein Abegaz  6   7 Akine Eshete Abosetugn  8 Abdelrahman I Abushouk  9 Oladimeji M Adebayo  10 Jose C Adsuar  11 Shailesh M Advani  12   13 Marcela Agudelo-Botero  14 Tauseef Ahmad  15   16 Muktar Beshir Ahmed  17 Rushdia Ahmed  18   19 Miloud Taki Eddine Aichour  20 Fares Alahdab  21 Fahad Mashhour Alanezi  22 Niguse Meles Alema  23 Biresaw Wassihun Alemu  24   25 Suliman A Alghnam  26 Beriwan Abdulqadir Ali  27 Saqib Ali  28 Cyrus Alinia  29 Vahid Alipour  30   31 Syed Mohamed Aljunid  32   33 Amir Almasi-Hashiani  34 Nihad A Almasri  35 Khalid Altirkawi  36 Yasser Sami Abdeldayem Amer  37   38 Catalina Liliana Andrei  39 Alireza Ansari-Moghaddam  40 Carl Abelardo T Antonio  41   42 Davood Anvari  43   44 Seth Christopher Yaw Appiah  45   46 Jalal Arabloo  30 Morteza Arab-Zozani  47 Zohreh Arefi  48 Olatunde Aremu  49 Filippo Ariani  50 Amit Arora  51   52 Malke Asaad  53 Beatriz Paulina Ayala Quintanilla  54   55 Getinet Ayano  56 Martin Amogre Ayanore  57 Ghasem Azarian  58 Alaa Badawi  59   60 Ashish D Badiye  61 Atif Amin Baig  62   63 Mohan Bairwa  64   65 Ahad Bakhtiari  66 Arun Balachandran  67   68 Maciej Banach  69   70 Srikanta K Banerjee  71 Palash Chandra Banik  72 Amrit Banstola  73 Suzanne Lyn Barker-Collo  74 Till Winfried Bärnighausen  75   76 Akbar Barzegar  77 Mohsen Bayati  78 Shahrzad Bazargan-Hejazi  79   80 Neeraj Bedi  81   82 Masoud Behzadifar  83 Habte Belete  84 Derrick A Bennett  85 Isabela M Bensenor  86 Kidanemaryam Berhe  87 Akshaya Srikanth Bhagavathula  88   89 Pankaj Bhardwaj  90   91 Anusha Ganapati Bhat  92 Krittika Bhattacharyya  93   94 Zulfiqar A Bhutta  95   96 Sadia Bibi  97 Ali Bijani  98 Archith Boloor  99 Guilherme Borges  100 Rohan Borschmann  101   102 Antonio Maria Borzì  103 Soufiane Boufous  104 Dejana Braithwaite  105 Nikolay Ivanovich Briko  106 Traolach Brugha  107 Shyam S Budhathoki  108 Josip Car  109   110 Rosario Cárdenas  111 Félix Carvalho  112 João Mauricio Castaldelli-Maia  113 Carlos A Castañeda-Orjuela  114   115 Giulio Castelpietra  116   117 Ferrán Catalá-López  118   119 Ester Cerin  120   121 Joht S Chandan  122 Jens Robert Chapman  123 Vijay Kumar Chattu  124 Soosanna Kumary Chattu  125 Irini Chatziralli  126   127 Neha Chaudhary  128   129 Daniel Youngwhan Cho  130 Jee-Young J Choi  131 Mohiuddin Ahsanul Kabir Chowdhury  132   133 Devasahayam J Christopher  134 Dinh-Toi Chu  135 Flavia M Cicuttini  136 João M Coelho  137 Vera M Costa  112 Saad M A Dahlawi  138 Ahmad Daryani  139 Claudio Alberto Dávila-Cervantes  140 Diego De Leo  141 Feleke Mekonnen Demeke  142 Gebre Teklemariam Demoz  143   144 Desalegn Getnet Demsie  23 Kebede Deribe  145   146 Rupak Desai  147 Mostafa Dianati Nasab  148 Diana Dias da Silva  149 Zahra Sadat Dibaji Forooshani  150 Hoa Thi Do  151 Kerrie E Doyle  152 Tim Robert Driscoll  153 Eleonora Dubljanin  154 Bereket Duko Adema  155   156 Arielle Wilder Eagan  157   158 Demelash Abewa Elemineh  159 Shaimaa I El-Jaafary  2 Ziad El-Khatib  160   161 Christian Lycke Ellingsen  162   163 Maysaa El Sayed Zaki  164 Sharareh Eskandarieh  165 Oghenowede Eyawo  166   167 Pawan Sirwan Faris  168   169 Andre Faro  170 Farshad Farzadfar  171 Seyed-Mohammad Fereshtehnejad  172   173 Eduarda Fernandes  174 Pietro Ferrara  175 Florian Fischer  176 Morenike Oluwatoyin Folayan  177 Artem Alekseevich Fomenkov  178 Masoud Foroutan  179 Joel Msafiri Francis  180 Richard Charles Franklin  181   182 Takeshi Fukumoto  183   184 Biniyam Sahiledengle Geberemariyam  185 Hadush Gebremariam  87 Ketema Bizuwork Gebremedhin  186 Leake G Gebremeskel  143   187 Gebreamlak Gebremedhn Gebremeskel  188   189 Berhe Gebremichael  190 Getnet Azeze Gedefaw  191   192 Birhanu Geta  193 Agegnehu Bante Getenet  194 Mansour Ghafourifard  195 Farhad Ghamari  196 Reza Ghanei Gheshlagh  197 Asadollah Gholamian  198   199 Syed Amir Gilani  200   201 Tiffany K Gill  202 Amir Hossein Goudarzian  203 Alessandra C Goulart  204   205 Ayman Grada  206 Michal Grivna  207 Rafael Alves Guimarães  208 Yuming Guo  136   209 Gaurav Gupta  210 Juanita A Haagsma  211 Brian James Hall  212 Randah R Hamadeh  213 Samer Hamidi  214 Demelash Woldeyohannes Handiso  185 Josep Maria Haro  215   216 Amir Hasanzadeh  217   218 Shoaib Hassan  219 Soheil Hassanipour  220   221 Hadi Hassankhani  222   223 Hamid Yimam Hassen  224   225 Rasmus Havmoeller  226 Delia Hendrie  56 Fatemeh Heydarpour  227 Martha Híjar  228   229 Hung Chak Ho  230 Chi Linh Hoang  231 Michael K Hole  232 Ramesh Holla  233 Naznin Hossain  234   235 Mehdi Hosseinzadeh  236   237 Sorin Hostiuc  238   239 Guoqing Hu  240 Segun Emmanuel Ibitoye  241 Olayinka Stephen Ilesanmi  242 Leeberk Raja Inbaraj  243 Seyed Sina Naghibi Irvani  244 M Mofizul Islam  245 Sheikh Mohammed Shariful Islam  246   247 Rebecca Q Ivers  248 Mohammad Ali Jahani  249 Mihajlo Jakovljevic  250 Farzad Jalilian  251 Sudha Jayaraman  252 Achala Upendra Jayatilleke  253   254 Ravi Prakash Jha  255 Yetunde O John-Akinola  256 Jost B Jonas  257   258 Kelly M Jones  259 Nitin Joseph  260 Farahnaz Joukar  220 Jacek Jerzy Jozwiak  261 Suresh Banayya Jungari  262 Mikk Jürisson  263 Ali Kabir  264 Amaha Kahsay  87 Leila R Kalankesh  265 Rohollah Kalhor  266   267 Teshome Abegaz Kamil  268 Tanuj Kanchan  269 Neeti Kapoor  61 Manoochehr Karami  270 Amir Kasaeian  271   272 Hagazi Gebremedhin Kassaye  23 Taras Kavetskyy  273   274 Gbenga A Kayode  275   276 Peter Njenga Keiyoro  277 Abraham Getachew Kelbore  278 Yousef Saleh Khader  279 Morteza Abdullatif Khafaie  280 Nauman Khalid  281 Ibrahim A Khalil  282 Rovshan Khalilov  283 Maseer Khan  284 Ejaz Ahmad Khan  285 Junaid Khan  286 Tripti Khanna  287   288 Salman Khazaei  270 Habibolah Khazaie  289 Roba Khundkar  290 Daniel N Kiirithio  291 Young-Eun Kim  292 Yun Jin Kim  293 Daniel Kim  294 Sezer Kisa  295 Adnan Kisa  296 Hamidreza Komaki  297   298 Shivakumar K M Kondlahalli  299 Ali Koolivand  300 Vladimir Andreevich Korshunov  106 Ai Koyanagi  301   302 Moritz U G Kraemer  303   304 Kewal Krishan  305 Barthelemy Kuate Defo  306   307 Burcu Kucuk Bicer  308   309 Nuworza Kugbey  310   311 Nithin Kumar  312 Manasi Kumar  313   314 Vivek Kumar  315 Narinder Kumar  316 Girikumar Kumaresh  317 Faris Hasan Lami  318 Van C Lansingh  319   320 Savita Lasrado  321 Arman Latifi  322 Paolo Lauriola  323 Carlo La Vecchia  324 Janet L Leasher  325 Shaun Wen Huey Lee  326   327 Shanshan Li  136 Xuefeng Liu  328 Alan D Lopez  1   102   329 Paulo A Lotufo  330 Ronan A Lyons  331 Daiane Borges Machado  332   333 Mohammed Madadin  334 Muhammed Magdy Abd El Razek  335 Narayan Bahadur Mahotra  336 Marek Majdan  337 Azeem Majeed  338 Venkatesh Maled  339   340 Deborah Carvalho Malta  341 Navid Manafi  342   343 Amir Manafi  344 Ana-Laura Manda  345 Narayana Manjunatha  346 Fariborz Mansour-Ghanaei  220 Mohammad Ali Mansournia  347 Joemer C Maravilla  348 Amanda J Mason-Jones  349 Seyedeh Zahra Masoumi  350 Benjamin Ballard Massenburg  130 Pallab K Maulik  351   352 Man Mohan Mehndiratta  353   354 Zeleke Aschalew Melketsedik  194 Peter T N Memiah  355 Walter Mendoza  356 Ritesh G Menezes  357 Melkamu Merid Mengesha  358 Tuomo J Meretoja  359   360 Atte Meretoja  361   362 Hayimro Edemealem Merie  363 Tomislav Mestrovic  364   365 Bartosz Miazgowski  366   367 Tomasz Miazgowski  368 Ted R Miller  56   369 G K Mini  370   371 Andreea Mirica  372   373 Erkin M Mirrakhimov  374   375 Mehdi Mirzaei-Alavijeh  251 Prasanna Mithra  260 Babak Moazen  376   377 Masoud Moghadaszadeh  378   379 Efat Mohamadi  380 Yousef Mohammad  381 Aso Mohammad Darwesh  382 Abdollah Mohammadian-Hafshejani  383 Reza Mohammadpourhodki  384 Shafiu Mohammed  75   385 Jemal Abdu Mohammed  386 Farnam Mohebi  171   387 Mohammad A Mohseni Bandpei  388 Mariam Molokhia  389 Lorenzo Monasta  390 Yoshan Moodley  391 Masoud Moradi  392   393 Ghobad Moradi  394   395 Maziar Moradi-Lakeh  396 Rahmatollah Moradzadeh  34 Lidia Morawska  397 Ilais Moreno Velásquez  398 Shane Douglas Morrison  130 Tilahun Belete Mossie  399 Atalay Goshu Muluneh  400 Kamarul Imran Musa  401 Ghulam Mustafa  402   403 Mehdi Naderi  404 Ahamarshan Jayaraman Nagarajan  405   406 Gurudatta Naik  407 Mukhammad David Naimzada  408   409 Farid Najafi  410 Vinay Nangia  411 Bruno Ramos Nascimento  412 Morteza Naserbakht  413   414 Vinod Nayak  415 Javad Nazari  416   417 Duduzile Edith Ndwandwe  418 Ionut Negoi  419   420 Josephine W Ngunjiri  421 Trang Huyen Nguyen  231 Cuong Tat Nguyen  422 Diep Ngoc Nguyen  423   424 Huong Lan Thi Nguyen  422 Rajan Nikbakhsh  425   426 Dina Nur Anggraini Ningrum  427   428 Chukwudi A Nnaji  418   429 Richard Ofori-Asenso  430   431 Felix Akpojene Ogbo  432 Onome Bright Oghenetega  433 In-Hwan Oh  434 Andrew T Olagunju  435   436 Tinuke O Olagunju  437 Ahmed Omar Bali  438 Obinna E Onwujekwe  439 Heather M Orpana  440   441 Erika Ota  442 Nikita Otstavnov  408   443 Stanislav S Otstavnov  408   444 Mahesh P A  445 Jagadish Rao Padubidri  446 Smita Pakhale  447 Keyvan Pakshir  448 Songhomitra Panda-Jonas  449 Eun-Kee Park  450 Sangram Kishor Patel  451   452 Ashish Pathak  453   454 Sanghamitra Pati  455 Kebreab Paulos  456 Amy E Peden  182   457 Veincent Christian Filipino Pepito  458 Jeevan Pereira  459 Michael R Phillips  460   461 Roman V Polibin  462 Suzanne Polinder  211 Farshad Pourmalek  463 Akram Pourshams  464 Hossein Poustchi  464 Swayam Prakash  465 Dimas Ria Angga Pribadi  466 Parul Puri  286 Zahiruddin Quazi Syed  91 Navid Rabiee  467 Mohammad Rabiee  468 Amir Radfar  469   470 Anwar Rafay  471 Ata Rafiee  472 Alireza Rafiei  473   474 Fakher Rahim  475   476 Siavash Rahimi  477 Muhammad Aziz Rahman  478   479 Ali Rajabpour-Sanati  480 Fatemeh Rajati  392 Ivo Rakovac  481 Sowmya J Rao  482 Vahid Rashedi  483 Prateek Rastogi  446 Priya Rathi  233 Salman Rawaf  338   484 Lal Rawal  485 Reza Rawassizadeh  486 Vishnu Renjith  487 Serge Resnikoff  488   489 Aziz Rezapour  30 Ana Isabel Ribeiro  490 Jennifer Rickard  491   492 Carlos Miguel Rios González  493   494 Leonardo Roever  495 Luca Ronfani  390 Gholamreza Roshandel  464   496 Basema Saddik  497 Hamid Safarpour  498 Mahdi Safdarian  499   500 S Mohammad Sajadi  501 Payman Salamati  500 Marwa R Rashad Salem  502 Hosni Salem  503 Inbal Salz  504 Abdallah M Samy  505 Juan Sanabria  506   507 Lidia Sanchez Riera  508   509 Milena M Santric Milicevic  510   511 Abdur Razzaque Sarker  512 Arash Sarveazad  513 Brijesh Sathian  514   515 Monika Sawhney  516 Mehdi Sayyah  517 David C Schwebel  518 Soraya Seedat  519 Subramanian Senthilkumaran  520 Seyedmojtaba Seyedmousavi  521 Feng Sha  522 Faramarz Shaahmadi  523 Saeed Shahabi  524 Masood Ali Shaikh  525 Mehran Shams-Beyranvand  526 Aziz Sheikh  527   528 Mika Shigematsu  529 Jae Il Shin  530   531 Rahman Shiri  532 Soraya Siabani  533   534 Inga Dora Sigfusdottir  535   536 Jasvinder A Singh  537   538 Pankaj Kumar Singh  539 Dhirendra Narain Sinha  540   541 Amin Soheili  542   543 Joan B Soriano  544   545 Muluken Bekele Sorrie  546 Ireneous N Soyiri  547   548 Mark A Stokes  549 Mu'awiyyah Babale Sufiyan  550 Bryan L Sykes  551 Rafael Tabarés-Seisdedos  552   553 Karen M Tabb  554 Biruk Wogayehu Taddele  555 Yonatal Mesfin Tefera  556   557 Arash Tehrani-Banihashemi  396   558 Gebretsadkan Hintsa Tekulu  559 Ayenew Kassie Tesema Tesema  560 Berhe Etsay Tesfay  561 Rekha Thapar  312 Mariya Vladimirovna Titova  178   562 Kenean Getaneh Tlaye  563 Hamid Reza Tohidinik  347   564 Roman Topor-Madry  565   566 Khanh Bao Tran  567   568 Bach Xuan Tran  569 Jaya Prasad Tripathy  90 Alexander C Tsai  570   571 Aristidis Tsatsakis  572 Lorainne Tudor Car  573 Irfan Ullah  574   575 Saif Ullah  97 Bhaskaran Unnikrishnan  260 Era Upadhyay  576 Olalekan A Uthman  577 Pascual R Valdez  578   579 Tommi Juhani Vasankari  580 Yousef Veisani  581 Narayanaswamy Venketasubramanian  582   583 Francesco S Violante  584   585 Vasily Vlassov  586 Yasir Waheed  587 Yuan-Pang Wang  113 Taweewat Wiangkham  588 Haileab Fekadu Wolde  400 Dawit Habte Woldeyes  589 Temesgen Gebeyehu Wondmeneh  386 Adam Belay Wondmieneh  186   590 Ai-Min Wu  591 Grant M A Wyper  592 Rajaram Yadav  286 Ali Yadollahpour  593 Yuichiro Yano  594 Sanni Yaya  595 Vahid Yazdi-Feyzabadi  596   597 Pengpeng Ye  598 Paul Yip  599   600 Engida Yisma  601 Naohiro Yonemoto  602 Seok-Jun Yoon  292 Yoosik Youm  603 Mustafa Z Younis  604   605 Zabihollah Yousefi  606   607 Chuanhua Yu  608   609 Yong Yu  610 Telma Zahirian Moghadam  30   611 Zoubida Zaidi  612 Sojib Bin Zaman  132   613 Mohammad Zamani  614 Hamed Zandian  611   615 Fatemeh Zarei  616 Zhi-Jiang Zhang  617 Yunquan Zhang  618   619 Arash Ziapour  533 Sanjay Zodpey  620 Rakhi Dandona  1   329   621 Samath Dhamminda Dharmaratne  1   329   622 Simon I Hay  1   329 Ali H Mokdad  1   329 David M Pigott  1   329 Robert C Reiner  1   329 Theo Vos  1   329
Affiliations

Estimating global injuries morbidity and mortality: methods and data used in the Global Burden of Disease 2017 study

Spencer L James et al. Inj Prev. 2020 Oct.

Abstract

Background: While there is a long history of measuring death and disability from injuries, modern research methods must account for the wide spectrum of disability that can occur in an injury, and must provide estimates with sufficient demographic, geographical and temporal detail to be useful for policy makers. The Global Burden of Disease (GBD) 2017 study used methods to provide highly detailed estimates of global injury burden that meet these criteria.

Methods: In this study, we report and discuss the methods used in GBD 2017 for injury morbidity and mortality burden estimation. In summary, these methods included estimating cause-specific mortality for every cause of injury, and then estimating incidence for every cause of injury. Non-fatal disability for each cause is then calculated based on the probabilities of suffering from different types of bodily injury experienced.

Results: GBD 2017 produced morbidity and mortality estimates for 38 causes of injury. Estimates were produced in terms of incidence, prevalence, years lived with disability, cause-specific mortality, years of life lost and disability-adjusted life-years for a 28-year period for 22 age groups, 195 countries and both sexes.

Conclusions: GBD 2017 demonstrated a complex and sophisticated series of analytical steps using the largest known database of morbidity and mortality data on injuries. GBD 2017 results should be used to help inform injury prevention policy making and resource allocation. We also identify important avenues for improving injury burden estimation in the future.

Keywords: descriptive epidemiology; methodology; populations/contexts; statistical issues.

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Conflict of interest statement

Competing interests: Dr. James reports grants from Sanofi Pasteur, outside the submitted work. Dr. Driscoll reports grants from World Health Organisation, during the conduct of the study. Dr Shariful Islam is funded by a Fellowship from National Heart Foundation of Australia and Institute for Physical Activity and Nutrition, Deakin University. Dr. Ivers reports grants from National Health and Medical Research Council of Australia, during the conduct of the study. Dr. Jozwiak reports personal fees from TEVA, personal fees from ALAB, personal fees from BOEHRINGER INGELHEIM, personal fees from SYNEXUS, non-financial support from SERVIER, non-financial support from MICROLIFE, non-financial support from MEDICOVER, outside the submitted work. Walter Mendoza is currently Program Analyst Population and Development at the Peru Country Office of the United Nations Population Fund-UNFPA, which does not necessarily endorses this study. Dr. Rakovac reports grants from World Health Organization, during the conduct of the study. Dr. Sheikh reports grants from Health Data Research UK, outside the submitted work. Dr. Singh reports personal fees from Crealta/Horizon, Medisys, Fidia, UBM LLC, Trio health, Medscape, WebMD, Clinical Care options, Clearview healthcare partners, Putnam associates, Spherix, Practice Point communications, the National Institutes of Health and the American College of Rheumatology, personal fees from Speaker’s bureau of Simply Speaking. Dr. Singh owns stock options in Amarin pharmaceuticals and Viking pharmaceuticals. Dr. Singh serves on the steering committee of OMERACT, an international organization that develops measures for clinical trials and receives arms-length funding from 12 pharmaceutical companies. Dr. Singh serves on the FDA Arthritis Advisory Committee. Dr. Singh is a member of the Veterans Affairs Rheumatology Field Advisory Committee. Dr. Singh is the editor and the Director of the UAB Cochrane Musculoskeletal Group Satellite Center on Network Meta-analysis, outside the submitted work. Dr. Stein reports personal fees from Lundbeck and Sun, outside the submitted work.

Figures

Figure 1
Figure 1
Cause of Death Ensemble model with data points for road injuries in Colombia for females.
Figure 2
Figure 2
Cause of Death Ensemble model with data points for road injuries in Honduras for females
Figure 3
Figure 3
Injuries non-fatal estimation flow chart.
Figure 4
Figure 4
Sexual violence estimation flow chart. HAQI, Healthcare Access and Quality Index.

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