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Review
. 2020 Dec;120(6):1289-1295.
doi: 10.1007/s13760-020-01472-6. Epub 2020 Aug 24.

Kennedy's disease: an under-recognized motor neuron disorder

Elia G Malek  1 , Johnny S Salameh  1 , Achraf Makki  2
Affiliations
Review

Kennedy's disease: an under-recognized motor neuron disorder

Elia G Malek et al. Acta Neurol Belg. 2020 Dec.

Abstract

Kennedy's disease or spinal bulbar muscular atrophy is a rare, inherited and slowly progressive multisystem disease mostly manifesting with a motor neuron disease phenotype leading to disability. The slow progression, partial androgen insensitivity, electrophysiological evidence of sensory neuronopathy, and relatively spared central nervous system pathways help differentiate it from amyotrophic lateral sclerosis. To date, there is no treatment or cure with clinical care mainly focused on accurate diagnosis, symptom management, patient education, and genetic counselling.

Keywords: Kennedy’s disease; Motor neuron disease; Spinal bulbar muscular atrophy.

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References

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