The long-term effects of prolonged intensive care stay postcardiac surgery
- PMID: 32840916
- DOI: 10.1111/jocs.14963
The long-term effects of prolonged intensive care stay postcardiac surgery
Abstract
Objectives: Short-term outcomes for those with a prolonged length of stay (LOS) in intensive care (ITU) following cardiac surgery are poor, with higher rates of in-hospital mortality and morbidity. Consequently, discharge from hospital has been considered the key measure of success. However, there has been a shift towards long-term outcomes, functional recovery and quality of life (QoL) as measures of surgical quality. The aim of this review is to compare and critique the findings of multiple studies to determine the long-term effects of prolonged ITU stay postcardiac surgery.
Methods: A computerized literature search of CINAHL, EMBASE and Google Scholar databases, based on keywords "long-term effects," "prolonged ITU stay," "cardiac surgery," with rigorous CASP critique was undertaken.
Results: The search yielded 12 papers meeting the inclusion criteria, with eight retrospective and four prospective studies. Eight of these 12 papers identified inferior long-term survival or higher mortality rates for those who had prolonged LOS in ITU in comparison to "normal" LOS or a control. The greatest burden of mortality was 6 months to 1 year postdischarge. Three papers found that quality of life was adversely affected or worse for those who had experienced prolonged LOS in ITU.
Conclusions: Further research is required to provide better quality evidence into QoL, following prolonged stay in ICU postcardiac surgery. The evidence reviewed suggests that the risk of mortality in this demographic of patients is higher, especially within the first year and, therefore, more frequent medical surveillance of these patients is recommended.
Keywords: cardiac surgery; critical care; intensive care; long-term outcomes.
© 2020 The Authors. Journal of Cardiac Surgery published by Wiley Periodicals LLC.
Similar articles
-
Effectiveness of dexmedetomidine versus propofol on extubation times, length of stay and mortality rates in adult cardiac surgery patients: a systematic review and meta-analysis.JBI Database System Rev Implement Rep. 2018 May;16(5):1220-1239. doi: 10.11124/JBISRIR-2017-003488. JBI Database System Rev Implement Rep. 2018. PMID: 29762314
-
Survival, Quality of Life, and Functional Status Following Prolonged ICU Stay in Cardiac Surgical Patients: A Systematic Review.Crit Care Med. 2019 Jan;47(1):e52-e63. doi: 10.1097/CCM.0000000000003504. Crit Care Med. 2019. PMID: 30398978
-
Outcomes of octogenarians discharged from the hospital after prolonged intensive care unit length of stay after cardiac surgery.J Thorac Cardiovasc Surg. 2017 Nov;154(5):1668-1678.e2. doi: 10.1016/j.jtcvs.2017.04.083. Epub 2017 Jul 6. J Thorac Cardiovasc Surg. 2017. PMID: 28688711
-
The influence of prolonged intensive care stay on quality of life, recovery, and clinical outcomes following cardiac surgery: A prospective cohort study.J Thorac Cardiovasc Surg. 2018 Nov;156(5):1906-1915.e3. doi: 10.1016/j.jtcvs.2018.05.076. Epub 2018 Jun 5. J Thorac Cardiovasc Surg. 2018. PMID: 30336918
-
Outcomes of Patients With Prolonged Intensive Care Unit Length of Stay After Cardiac Surgery.J Cardiothorac Vasc Anesth. 2016 Dec;30(6):1550-1554. doi: 10.1053/j.jvca.2016.03.145. Epub 2016 Mar 23. J Cardiothorac Vasc Anesth. 2016. PMID: 27498267
Cited by
-
Associations Between Physical, Cognitive, and Mental Health Domains of Post-Intensive Care Syndrome and Quality of Life: A Longitudinal Multicenter Cohort Study.Crit Care Med. 2025 Jan 1;53(1):e74-e86. doi: 10.1097/CCM.0000000000006461. Epub 2024 Oct 24. Crit Care Med. 2025. PMID: 39445920 Free PMC article.
-
Albumin Infusion in Critically Ill COVID-19 Patients: Hemodilution and Anticoagulation.Int J Mol Sci. 2021 Jul 1;22(13):7126. doi: 10.3390/ijms22137126. Int J Mol Sci. 2021. PMID: 34281177 Free PMC article. Review.
-
Extended length of stay after elective ascending aortic surgery and associated risk factors.North Clin Istanb. 2022 Oct 24;9(5):445-450. doi: 10.14744/nci.2021.27037. eCollection 2022. North Clin Istanb. 2022. PMID: 36447589 Free PMC article.
-
Laparoscopy in high-risk emergency general surgery reduces intensive care stay, length of stay and mortality.Langenbecks Arch Surg. 2023 Jan 24;408(1):62. doi: 10.1007/s00423-022-02744-w. Langenbecks Arch Surg. 2023. PMID: 36692646 Free PMC article.
References
REFERENCES
-
- Stephens R, Whitman G. Postoperative critical care of the adult cardiac surgical patient. Crit Care Med. 2015;43(9):1995-2014.
-
- Kapadohos T, Angelopoulos E, Vasileiadis I, et al. Determinants of prolonged intensive care unit stay in patients after cardiac surgery: a prospective observational study. J Thorac Dis. 2017;9(1):70-79.
-
- Barrie K, Cornick A, Debreuil S, et al. Patients with a prolonged intensive care unit length of stay have decreased health-related quality of life after cardiac surgery. Semin Thorac Cardiovasc Surg. 2019;31(1):21-31.
-
- Diab M, Bilkhu R, Soppa G, et al. Quality of life in relation to length of intensive care unit stay after cardiac surgery. J Cardiothorac Vasc Anesth. 2017;31(3):1080-1090.
-
- Hein O, Birnbaum J, Wernecke K, England M, Konertz W, Spies C. Prolonged intensive care unit stay in cardiac surgery: risk factors and long-term-survival. Ann Thorac Surg. 2006;81(3):880-885.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Medical