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. 2020 Aug 26:148:e189.
doi: 10.1017/S0950268820001910.

Frequency of five unusual presentations in patients with COVID-19: results of the UMC-19-S1

Òscar Miró  1 , Pere Llorens  2 , Sònia Jiménez  1 , Pascual Piñera  3 , Guillermo Burillo-Putze  4 , Alfonso Martín  5 , Francisco Javier Martín-Sánchez  6 , Juan González Del Castillo  6 ; Spanish Investigators in Emergency Situations TeAm (SIESTA) network
Affiliations

Frequency of five unusual presentations in patients with COVID-19: results of the UMC-19-S1

Òscar Miró et al. Epidemiol Infect. .

Abstract

Despite SARS-CoV-19 infection has a stereotypical clinical picture, isolated cases with unusual manifestations have been reported, some of them being well-known to be triggered by viral infections. However, the real frequency in COVID-19 is unknown. Analysing data of 63 822 COVID patients attending 50 Spanish emergency department (ED) during the COVID outbreak, before hospitalisation, we report frequencies of (myo)pericarditis (0.71‰), meningoencephalitis (0.25‰), Guillain-Barré syndrome (0.13‰), acute pancreatitis (0.71‰) and spontaneous pneumothorax (0.57‰). Compared with general ED population, COVID patients developed more frequently Guillain-Barré syndrome (odds ratio (OR) 4.55, 95% confidence interval (CI) 2.09-9.90), spontaneous pneumothorax (OR 1.98, 95% CI 1.40-2.79) and (myo)pericarditis (OR 1.45, 95% CI 1.07-1.97), but less frequently pancreatitis (OR 0.44, 95% CI 0.33-0.60).

Keywords: COVID; Guillain–Barré syndrome; SARS-CoV-2; meningoencephalitis; myopericarditis; pancreatitis; spontaneous pneumothorax.

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Conflict of interest statement

None author reported any conflict of interest directly or indirectly connected with this manuscript.

Figures

Fig. 1.
Fig. 1.
Comparison of the incidence of the five unusual manifestations evaluated in patients with COVID-19 compared with non-COVID patients.
See this image and copyright information in PMC

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