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Case Reports
. 2020 Aug 24;13(8):e235387.
doi: 10.1136/bcr-2020-235387.

Vasospasm induced myocardial ischaemia secondary to sumatriptan use

Kenneth Okonkwo  1 , Utkarsh Ojha  2
Affiliations
Case Reports

Vasospasm induced myocardial ischaemia secondary to sumatriptan use

Kenneth Okonkwo et al. BMJ Case Rep. .

Abstract

Certain medications have been implicated in causing acute myocardial infarctions (AMI). Sumatriptan, a medication usually prescribed for acute migraine and cluster headaches has been documented as potentially causing coronary vasospasm, thereby leading to MI. This is usually seen in patients with strong risk factors for coronary artery disease (CAD) or in those with established CAD. Most cases thus far have been reported in patients using the subcutaneous preparation of sumatriptan. Here, we present a case of a patient without prior risk factors for CAD and angiographically unremarkable coronary arteries who presented with evidence of an AMI after oral sumatriptan use for migraines.

Keywords: cardiovascular medicine; ischaemic heart disease; pharmacology and therapeutics.

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Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1
ECG on presentation.
Figure 2
Figure 2
ECG 2 hours after presentation; deepening T-waves in V2–V5.
Figure 3
Figure 3
ECG on day 3 of admission; prominent T-wave inversions in leads I, II III, aVL and aVF.
Figure 4
Figure 4
Angiogram showing patent coronary arteries.
See this image and copyright information in PMC

References

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