Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020:5:580-587.
doi: 10.1016/j.idm.2020.08.004. Epub 2020 Aug 17.

Evaluation of the effect of the state of emergency for the first wave of COVID-19 in Japan

Affiliations

Evaluation of the effect of the state of emergency for the first wave of COVID-19 in Japan

Toshikazu Kuniya. Infect Dis Model. 2020.

Abstract

In this paper, we evaluate the effect of the state of emergency for the first wave of COVID-19 in Japan, 2020 from the viewpoint of mathematical modelling. In Japan, it was announced during the period of the state of emergency from April 7 to May 25, 2020 that the 80% reduction of the contact rate is needed to control the outbreak. By numerical simulation, we show that the reduction rate seems to have reached up to 86%. Moreover, we estimate the control reproduction number R c during the period of the state of emergency as R c = 0.36 (95%CI, 0.34-0.39), and show that the effective reproduction number R e after the lifting of the state of emergency could be greater than 1. This result suggests us that the second wave of COVID-19 in Japan could possibly occur if any effective intervention will not be taken again.

Keywords: Basic reproduction number; COVID-19; SEIR epidemic model; State of emergency.

PubMed Disclaimer

Conflict of interest statement

The author declares no conflict of interest.

Figures

Fig. 1
Fig. 1
Daily number of newly reported cases of COVID-19 in Japan from January 15 to June 30, 2020. The start and end of the state of emergency (SOE) are on April 7 and May 25, 2020, respectively.
Fig. 2
Fig. 2
Comparison of the actual data of COVID-19 in Japan, 2020 and the predicted epidemic curve for R0=2.6 (95%CI, 2.4–2.8), which was estimated in (Kuniya, 2020) using the early data (from January 15 to February 29, 2020).
Fig. 3
Fig. 3
Transfer diagram for the SEIR model.
Fig. 4
Fig. 4
The weighted least square function L(k) versus 0<k<1.
Fig. 5
Fig. 5
Comparison of the daily number of newly reported cases of COVID-19 in Japan, 2020 and the estimated epidemic curve with model (1) for tT1 and model (2) for tT2 (k=0.14).
Fig. 6
Fig. 6
(a) The weighted least square function L2(k2) versus 0<k2<1; (b) Comparison of the daily number of newly reported cases of COVID-19 in Japan, 2020 and the estimated epidemic curve with model (1) for tT1, model (2) for tT2 and model (3) for tT3(167,365] (k=0.14 and k2=0.45).

References

    1. Anderson R.M., Heesterbeek H., Kilnkenberg D. How will country-based mitigation measures influence the course of the COVID-19 epidemic? The Lancet. 2020;395:931–934. - PMC - PubMed
    1. Bommer C., Vollmer S. Average detection rate of SARS-CoV-2 infections is estimated around six percent. 2020. https://www.uni-goettingen.de/en/606540.html
    1. Capaldi A., Behrend S., Berman B. Parameter estimation and uncertainty quantification for an epidemic model. Mathematical Biosciences and Engineering. 2012;9:553–576. - PubMed
    1. Chen Z., Yang J., Dai B. Forecast possible risk for COVID-19 epidemic dissemination under current control strategies in Japan. International Journal of Environmental Research and Public Health. 2020;17:3872. - PMC - PubMed
    1. Crokidakis N. COVID-19 spreading in Rio de Janeiro, Brazil: Do the policies of social isolation really work? Chaos, Solitons & Fractals. 2020;136:109930. - PMC - PubMed

LinkOut - more resources