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Review
. 2020 Aug 26;22(10):60.
doi: 10.1007/s11926-020-00945-0.

Vasculitides in HIV Infection

Luis E Vega  1 , Luis R Espinoza  2
Affiliations
Review

Vasculitides in HIV Infection

Luis E Vega et al. Curr Rheumatol Rep. .

Abstract

Purpose of review: To review the spectrum of vasculitides in HIV-infected patients and to identify the clinical features that characterize vasculitis in sero-positive HIV.

Recent findings: Epidemiological studies conducted in the post-HAART era described the rarity of vasculitis in the setting of HIV-infected patients. A study identified histopathological features such as leukocytoclastic vasculitis of the vasa vasorum and adventitial inflammation in the large artery pathology of HIV-positive patients compared with HIV-negative patients with critical lower limb ischemia. A recent retrospective cohort study reported that HIV-positive patients with LVV developed more vascular complications, responded less to antiretroviral therapy, and had worse outcome than HIV-negative patients with LVV. Vasculitides continue to be a rare disease in patients with HIV. The spectrum of vasculitis ranges from life-threatening conditions to relatively mild skin conditions. Recognizing vasculitis in the setting of HIV-positive patients is important because sometimes it require immunosuppressive treatment.

Keywords: HIV infection; Kawasaki-like syndrome; Large-vessel vasculitis; Polyarteritis nodosa; Vasculitides.

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Conflict of interest statement

The authors declare that they have no conflict of interest.

Figures

Fig. 1
Fig. 1
Mechanisms to induce HIV infection
See this image and copyright information in PMC

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