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. 2011 Nov;16(4):218-221.
doi: 10.1111/j.1475-3588.2011.00610.x. Epub 2011 Jun 15.

Antipsychotic prescribing: old wine in new bottles?

Shermin Imran  1 , Soumitra Shankar Datta  2 , Elaine Vincent  1 , Jade Whitfield  1 , Andrew F Clark  1
Affiliations

Antipsychotic prescribing: old wine in new bottles?

Shermin Imran et al. Child Adolesc Ment Health. 2011 Nov.

Abstract

Background: Recent research suggests first generation antipsychotic medications may be no less effective or tolerated than second generation antipsychotics.

Aims: To review prescribing practices in UK adolescent mental health settings.

Method: A review of literature and a postal survey (structured questionnaire) of clinicians in UK adolescent mental health settings (80 general and specialised in-patient units) were conducted.

Results: Second generation antipsychotics remain the drug of first choice for most UK clinicians (based on a survey response rate of 40%).

Conclusions: Guidelines for antipsychotic use in adolescents need updating. Clinicians who qualified in the last 10 years may need specific training and experience in use of first generation antipsychotics.

Keywords: Adolescence; pharmacology; psychiatric practice; psychosis.

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References

    1. Clark, A.F. (2004). Incidences of new prescribing by British child and adolescent psychiatrists: A prospective study over 12 months. Journal of Psychopharmacology, 18, 115-120.
    1. Correll, C.U., Manu, P., Olshanskiy, V., Napolitano, B., Kane, J.M., & Malhotra, A.K. (2009). Cardiometabolic risk of second-generation antipsychotic medications during first-time use in children and adolescents. Journal of the American Medical Association, 302, 1765-1773.
    1. Crossley, N.A., Constante, M., McGuire, P., & Power, P. (2010). Efficacy of atypical v. typical antipsychotics in the treatment of early psychosis: Meta-analysis. British Journal of Psychiatry, 196, 434-439.
    1. Department of Health (2006). Improving patients’ access to medicines: A guide to implementing nurse and pharmacist independent prescribing within the NHS in England. Gateway reference 6429. London: Department of Health.
    1. Hughes, L., & Wilson, J. (1986). Social work on the bridge. In D. Steinberg, The adolescent unit: Work and teamwork in adolescent psychiatry (pp. 1-18). Chichester: John Wiley & Sons.

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