Fasting-mimicking diet plus chemotherapy in breast cancer treatment
- PMID: 32848145
- PMCID: PMC7450058
- DOI: 10.1038/s41467-020-18194-1
Fasting-mimicking diet plus chemotherapy in breast cancer treatment
Abstract
A clinical trial published in Nature Communications examined the effect of fasting-mimicking diet (FMD) during chemotherapy in breast cancer patients. The overall negative study results highlight the need for ameliorating future trial design and investigating alternative FMD-based therapeutic combinations.
Conflict of interest statement
C.V., L.R. and F.deB. were inventors of an FMD regimen that is being evaluated in the context of ongoing clinical trials in cancer patients.
Comment on
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Fasting mimicking diet as an adjunct to neoadjuvant chemotherapy for breast cancer in the multicentre randomized phase 2 DIRECT trial.Nat Commun. 2020 Jun 23;11(1):3083. doi: 10.1038/s41467-020-16138-3. Nat Commun. 2020. PMID: 32576828 Free PMC article. Clinical Trial.