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Review
. 2020 Aug 11:15:5951-5961.
doi: 10.2147/IJN.S255784. eCollection 2020.

Green Synthesis of Cerium Oxide Nanoparticles (CeO2 NPs) and Their Antimicrobial Applications: A Review

Muhammad Nadeem  1 , Ramsha Khan  1 , Komal Afridi  1 , Akhtar Nadhman  1 , Sana Ullah  2 , Sulaiman Faisal  1 , Zia Ul Mabood  1 , Christophe Hano  3 , Bilal Haider Abbasi  2
Affiliations
Review

Green Synthesis of Cerium Oxide Nanoparticles (CeO2 NPs) and Their Antimicrobial Applications: A Review

Muhammad Nadeem et al. Int J Nanomedicine. .

Abstract

During the last decade green synthesized cerium oxide nanoparticles (CeO2 NPs) attracted remarkable interest in various fields of science and technology. This review, explores the vast array of biological resources such as plants, microbes, and other biological products being used in synthesis of CeO2 NPs. It also discusses their biosynthetic mechanism, current understandings, and trends in the green synthesis of CeO2 NPs. Novel therapies based on green synthesized CeO2 NPs are illustrated, in particular their antimicrobial potential along with attempts of their mechanistic elucidation. Overall, the main objective of this review is to provide a rational insight of the major accomplishments of CeO2 NPs as novel therapeutics agents for a wide range of microbial pathogens and combating other diseases.

Keywords: antimicrobial; biomedical; cerium oxide; green synthesis; infections; nanoparticles; nanotechnology.

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Conflict of interest statement

The authors report no conflicts of interest for this work.

Figures

Figure 1
Figure 1
General applications of CeO2 nanoparticles.
Figure 2
Figure 2
Biosynthesis: Reduction, stabilization and characterization of CeO2 nanoparticles.
Figure 3
Figure 3
Schematic representation of antibacterial activity of CeO2 nanoparticles. (1) Cell wall disruption; (2) Cell membrane disintegration; (3) Free radicals productions; (4) Loss of protein peptides; (5) DNA fragmentation; (6) Vital enzymes inhibition; (7) Loss of cellular fluids; and (8) Disruption in electron transport.
See this image and copyright information in PMC

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