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Review
. 2020 Jun 14;10(3):269-272.
doi: 10.1080/20009666.2020.1761185.

Diagnosis and management of tumor lysis syndrome

Isha Puri  1 , Deep Sharma  2 , Krishna S Gunturu  3 , Andaleeb A Ahmed  4
Affiliations
Review

Diagnosis and management of tumor lysis syndrome

Isha Puri et al. J Community Hosp Intern Med Perspect. .

Abstract

Tumor lysis syndrome (TLS) is an oncological emergency characterized by a classic tetrad of hyperuricemia, hyperkalemia, hyperphosphatemia, and hypocalcemia. Risk assessment and prophylactic therapy is critical in preventing this oncological emergency. Treatment of established TLS involves aggressive hydration, electrolyte management, and the use of hypouricemic agents.

Keywords: Tumor lysis syndrome; cancer; malignancy; tumor; uric acid.

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Conflict of interest statement

The authors have no financial relationships relevant to this article to disclose.

Figures

Figure 1.
Figure 1.
Risk factors and diagnosis of Tumor Lysis Syndrome.
Figure 2.
Figure 2.
Pathophysiology and clinical manifestations of Tumor Lysis Syndrome.
See this image and copyright information in PMC

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