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Review
. 2020 Sep;11(5):619-624.
doi: 10.1177/2150135120934763.

Monocusp Valves Do Not Improve Early Operative Mortality in Tetralogy of Fallot: A Meta-Analysis

Mark N Awori  1 , Jonathan A Awori  2 , Nikita P Mehta  1 , Obed Makori  1
Affiliations
Review

Monocusp Valves Do Not Improve Early Operative Mortality in Tetralogy of Fallot: A Meta-Analysis

Mark N Awori et al. World J Pediatr Congenit Heart Surg. 2020 Sep.

Abstract

Monocusp valves are thought to reduce early operative mortality and morbidity associated with pediatric tetralogy of Fallot repair. As there are no published randomized clinical trials comparing outcomes with and without a monocusp valve, we performed a meta-analysis of observational studies in accordance with established protocols. After systematically searching PubMed, the Cochrane Library, and Google Scholar, 12 studies were included. The operative mortality was compared in 695 patients, and we found no difference between patients with and patients without a monocusp valve. Monocusp valves may not improve operative mortality of tetralogy of Fallot repair in pediatric patients.

Keywords: monocusp valve; mortality; pediatric; tetralogy of Fallot.

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Comment in

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    Cleveland JD, Kumar SR. Cleveland JD, et al. World J Pediatr Congenit Heart Surg. 2020 Sep;11(5):625-626. doi: 10.1177/2150135120940619. World J Pediatr Congenit Heart Surg. 2020. PMID: 32853060 No abstract available.

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