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. 2020 Dec;81(6):e4-e6.
doi: 10.1016/j.jinf.2020.08.029. Epub 2020 Aug 25.

Post-discharge persistent symptoms and health-related quality of life after hospitalization for COVID-19

Eve Garrigues  1 , Paul Janvier  2 , Yousra Kherabi  1 , Audrey Le Bot  1 , Antoine Hamon  1 , Hélène Gouze  1 , Lucile Doucet  1 , Sabryne Berkani  1 , Emma Oliosi  1 , Elise Mallart  1 , Félix Corre  1 , Virginie Zarrouk  1 , Jean-Denis Moyer  3 , Adrien Galy  1 , Vasco Honsel  1 , Bruno Fantin  1 , Yann Nguyen  4
Affiliations

Post-discharge persistent symptoms and health-related quality of life after hospitalization for COVID-19

Eve Garrigues et al. J Infect. 2020 Dec.

Abstract

Objective: To assess post-discharge persistent symptoms and health-related quality of life (HRQoL) of patients hospitalized in a COVID-19 ward unit more than 100 days after their admission.

Methods: All eligible patients were contacted by phone by trained physicians and were asked to answer to a dedicated questionnaire. Patients managed in hospital ward without needing intensive care were compared with those who were transferred in intensive care units (ICU).

Results: We included 120 patients after a mean (±SD) of 110.9 (±11.1) days following admission. The most frequently reported persistent symptoms were fatigue (55%), dyspnoea (42%), loss of memory (34%), concentration and sleep disorders (28% and 30.8%, respectively). Comparisons between ward- and ICU patients led to no statistically significant differences regarding those symptoms. In both group, EQ-5D (mobility, self-care, pain, anxiety or depression, usual activity) was altered with a slight difference in pain in the ICU group.

Conclusion: Most patients requiring hospitalization for COVID-19 still have persistent symptoms. While there were few differences between HRQoL between ward and ICU patients, our findings must be confirmed in larger cohorts, including more severe patients.

Keywords: Covid-19; Health-related quality of life; Persistent symptoms.

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Conflict of interest statement

Declaration of Competing Interest None of the authors declared any competing interest in link with the present study.

Figures

Fig. 1
Fig. 1
Health-related quality of life after hospitalization for COVID-19 assessed by the EQ-5D 5 L in the ward and the ICU groups. 1A: Distribution of the EQ-5D index (0: death to 1: full health). 1B: EQ-5D 5 L scores in the ward and in the ICU groups on each domain. Each domain is scored on a 5-point scale: 1 no problem, 2 slight problem, 3 moderate problem, 4 severe problem, 5 unable to do. *: P = 0.032.
See this image and copyright information in PMC

Comment in

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