Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Aug 27;13(1):399.
doi: 10.1186/s13104-020-05241-9.

Impact of COVID-19 pandemic and the lockdown on invasive meningococcal disease

Muhamed-Kheir Taha  1 , Ala-Eddine Deghmane  2
Affiliations
Free PMC article

Impact of COVID-19 pandemic and the lockdown on invasive meningococcal disease

Muhamed-Kheir Taha et al. BMC Res Notes. .
Free PMC article

Abstract

Objective: Few data are available on the association between SARS-CoV-2 and secondary bacterial infections. Such an association was described for flu and invasive meningococcal disease (IMD). We aimed exploring such a correlation between COVID-19 and IMD as well as the impact of the lockdown on IMD.

Results: We compared IMD cases received at the French National Reference Centre for meningococci and Haemophilus influenzae that are sent as part of the mandatory reporting of IMD. We compared these data during the period 01 January-15 May 2020 to those from the same period in 2018 and 2019. IMD cases that were associated with respiratory presentations significantly increased in 2020 compared to 2018 (P = 0.029) and 2019 (P = 0.002), involved elderly and were due to unusual isolates. However, IMD cases due to hyperinvasive isolates decreased during the lockdown. Enhancing IMD surveillance and anti-meningococcal vaccination in elderly should be addressed.

Keywords: Infection; Invasive meningococcal disease; Respiratory presentations; SARS-CoV-2, COVID-19; Typing.

PubMed Disclaimer

References

    1. J Allergy Clin Immunol. 2020 Jul;146(1):215-217 - PubMed
    1. J Clin Microbiol. 2004 Nov;42(11):5146-53 - PubMed
    1. J Infect. 2018 Feb;76(2):149-158 - PubMed
    1. Lancet. 2020 Mar 28;395(10229):1054-1062 - PubMed
    1. Lancet Infect Dis. 2006 May;6(5):303-12 - PubMed

MeSH terms