Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2020 Aug;88(Suppl 1):56-59.
doi: 10.1038/s41390-020-1081-5.

Opportunities for the federal government to advance necrotizing enterocolitis research

Affiliations
Review

Opportunities for the federal government to advance necrotizing enterocolitis research

Samir K Gadepalli et al. Pediatr Res. 2020 Aug.

Abstract

Background: Necrotizing enterocolitis (NEC) is a leading cause of morbidity and mortality in the neonatal ICU with minimal progress in the research.

Methods: Federal webpages were queried to look for funding opportunity announcements (FOAs) and to develop lists of funded projects on NEC to identify gaps in NEC-related research topics.

Results: Over the past 30 years, the National Institutes of Health (NIH) issued two FOAs to stimulate research on NEC with $4.1 million set aside for the first year of respective funding. We identified 23 recently funded studies of which 18 were research projects, 4 training grants, and 1 conference grant support. Only one grant focused on parent and family engagement in the NICU.

Conclusion: There are significant research gaps that can be addressed with adequate funding from the federal government on the prevention and treatment of NEC.

PubMed Disclaimer

References

    1. Blakely, M. L. et al. Postoperative outcomes of extremely low birth-weight infants with necrotizing enterocolitis or isolated intestinal perforation: a prospective cohort study by the NICHD Neonatal Research Network. Ann. Surg. 241, 984–989 (2005). Discussion 989–994. - DOI
    1. Horbar, J. D. et al. Variation in performance of neonatal intensive care units in the United States. JAMA Pediatrics 171, e164396 (2017). - DOI
    1. Patel, R. M. et al. Causes and timing of death in extremely premature infants from 2000 through 2011. N. Engl. J. Med. 372, 331–340 (2015). - DOI
    1. Gadepalli, S. K. et al. Roles and experiences of parents in necrotizing enterocolitis: an international survey of parental perspectives of communication in the NICU”. Adv. Neonatal Care 17, 489–498 (2017). - DOI
    1. US Department of Health and Human Services. NIH RePORTER - NIH Research Portfolio Online Reporting Tools Expenditures and Results. https://report.nih.gov/ (2019). Accessed 14 Jun 2019.

Publication types

LinkOut - more resources