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. 2020 Sep;297(1):5-12.
doi: 10.1111/imr.12912.

Intracellular innate immune receptors: Life inside the cell

Thirumala-Devi Kanneganti  1
Affiliations

Intracellular innate immune receptors: Life inside the cell

Thirumala-Devi Kanneganti. Immunol Rev. 2020 Sep.
No abstract available

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Conflict of interest statement

Conflict of interest

The author declares no conflict of interest.

Figures

Figure 1
Figure 1
Intracellular innate immune sensors and their downstream signaling pathways. This figure provides a graphical summary of the reviews in this collection and depicts the various cytosolic and nuclear pattern recognition receptors that are discussed, along with their key signaling pathways. AIM2, absent in melanoma 2; ASC, apoptosis-associated speck-like protein containing a CARD; CARD, caspase activation and recruitment domain; CASP, caspase; FADD, fas-associated death domain; GBPs, guanylate binding proteins; GSDMD, gasdermin D; MDA5, melanoma differentiation-associated protein 5; MLKL, mixed lineage kinase domain-like pseudokinase; IRF, interferon regulatory factor; NLRs, nucleotide-binding domain, leucine-rich repeat-containing (or NOD-like) receptors; pMLKL, phospho-MLKL; RIG-I, retinoic acid-inducible gene I; RIPK, receptor-interacting serine/threonine-protein kinase; TLRs, Toll-like receptors; ZBP1, Z-DNA-binding protein 1
See this image and copyright information in PMC

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