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Comment
. 2020 Sep 14;38(3):320-322.
doi: 10.1016/j.ccell.2020.07.011. Epub 2020 Aug 27.

Mastering the Complex Targeted Therapy for Non-small Cell Lung Cancer

Siddhartha Devarakonda  1 , Ramaswamy Govindan  1 , Daniel Morgensztern  2
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Mastering the Complex Targeted Therapy for Non-small Cell Lung Cancer

Siddhartha Devarakonda et al. Cancer Cell. .
Free article

Abstract

In a recent Nature article, Middleton et al. report the National Lung Matrix trial results where patients with previously treated non-small cell lung cancer (NSCLC) are assigned to personalized therapy based on the results of a 28-gene next-generation sequencing panel test.

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  • The National Lung Matrix Trial of personalized therapy in lung cancer.
    Middleton G, Fletcher P, Popat S, Savage J, Summers Y, Greystoke A, Gilligan D, Cave J, O'Rourke N, Brewster A, Toy E, Spicer J, Jain P, Dangoor A, Mackean M, Forster M, Farley A, Wherton D, Mehmi M, Sharpe R, Mills TC, Cerone MA, Yap TA, Watkins TBK, Lim E, Swanton C, Billingham L. Middleton G, et al. Nature. 2020 Jul;583(7818):807-812. doi: 10.1038/s41586-020-2481-8. Epub 2020 Jul 15. Nature. 2020. PMID: 32669708 Free PMC article. Clinical Trial.

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