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Review
. 2021 Feb 1;38(2):130-137.
doi: 10.1097/EJA.0000000000001297.

Long-term psychological and physical outcomes of women after postdural puncture headache: A retrospective, cohort study

Sharon Orbach-Zinger  1 , Leonid A Eidelman, Michal Y Livne, Olya Matkovski, Eitan Mangoubi, Adi Borovich, Susan A Wazwaz, Alexander Ioscovich, Zoya Haitov Ben Zekry, Karin Ariche, Carolyn F Weiniger
Affiliations
Review

Long-term psychological and physical outcomes of women after postdural puncture headache: A retrospective, cohort study

Sharon Orbach-Zinger et al. Eur J Anaesthesiol. .

Abstract

Background: Postdural puncture headache after accidental dural puncture during labour may lead to chronic sequalae.

Objectives: We aimed to measure the incidence of postpartum depression, posttraumatic stress disorder, chronic headache, backache and breastfeeding rates after a postdural puncture headache.

Design: A retrospective, case-matched cohort study.

Setting: A review of documented cases of dural puncture and matched case controls occurring at Rabin Medical Center and Shamir Medical Center from 01 January 2012 to 30 September 2018.

Patients: The study cohort consisted of women with a documented postdural puncture headache and the controls were women with uneventful labour epidurals in the same 24-h period. Women were interviewed by telephone.

Primary outcomes measure: The primary outcome measure was the incidence of postpartum depression after a postdural puncture headache.

Results: Women with postdural puncture headache (n = 132) and controls (n = 276) had similar demographic data. The incidence of postpartum depression was 67/128 (52.3%) versus 31/276 (11.2%) for controls, P < 0.0001, 95% confidence intervals of the difference 31.5 to 50.2. Posttraumatic stress disorder was more frequent among women with postdural puncture headache, 17/132 (12.8%) versus controls 1/276 (0.4%), P < 0.0001, 95% confidence intervals of the difference 7.6 to 19.5. Women with postdural puncture headache breastfed less, 74/126 (54.5%) versus controls 212/276 (76.8%), P < 0.0001, 95% confidence intervals of the difference 33.1 to 55.2. Current headache and backache were significantly more frequent among women with postdural puncture headache [current headache 42/129 (32.6%) versus controls 42/276 (15.2%) P < 0.00001, 95% confidence intervals 0.085 to 0.266; current backache 58/129 (43.9%) versus controls 58/275 (21%) P < 0.0001, 95% confidence intervals 14.1 to 33.5].

Conclusion: We report an increased incidence of postpartum depression, posttraumatic stress disorder, chronic headache and backache and decreased breastfeeding following a postdural puncture headache. Our findings emphasise the need for postpartum follow-up for women with postdural puncture headache.

Trial registry number: Clinical trial registry number: NCT03550586.

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References

    1. Bradbury CL, Singh SI, Badder SR, et al. Prevention of postdural puncture headache in parturients: a systematic review and meta-analysis. Acta Anaesthesiol Scand 2013; 57:417–430.
    1. Berger CW, Crosby ET, Grodecki W. North American survey of the management of dural puncture occurring during labour epidural analgesia. Can J Anaesth 1998; 45:110–114.
    1. Orbach-Zinger S, Ashwal E, Hazan L, et al. Risk factors for unintended dural puncture in obstetric patients: a retrospective cohort study. Anesth Analg 2016; 123:972–976.
    1. Paech MJ, Doherty DA, Christmas T, Wong CA. The volume of blood for epidural blood patch in obstetrics: a randomized, blinded clinical trial. Anesth Analg 2011; 113:126–133.
    1. Van de Velde M, Schepers R, Berends N, et al. Ten years of experience with accidental dural puncture and postdural puncture headache in a tertiary obstetric anaesthesia department. Int J Obstet Anaesth 2008; 17:329–335.

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