Very high-risk familial hypercholesterolaemia patients in real life: The remaining gap in achieving the current LDL-C targets despite the use of PCSK9 inhibitors

Affiliations

¹ 2nd Department of Cardiology, Medical School, National and Kapodistrian University of Athens, Attikon University Hospital, Athens, Greece. Electronic address: lrallidis@gmail.com.
² Department of Internal Medicine, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, Greece.
³ 1st Department of Cardiology, Medical School, National and Kapodistrian University of Athens, Hippokration Hospital, Athens, Greece.
⁴ Cardiometabolic Center, Lipoprotein Apheresis and Lipid Disorders Clinic, Metropolitan Hospital, Athens, Greece.
⁵ 2nd Department of Cardiology, Medical School, National and Kapodistrian University of Athens, Attikon University Hospital, Athens, Greece.

Comment

Loukianos S Rallidis et al. Atherosclerosis. 2020 Sep.

. 2020 Sep:309:67-69.

doi: 10.1016/j.atherosclerosis.2020.07.018. Epub 2020 Jul 30.

¹ 2nd Department of Cardiology, Medical School, National and Kapodistrian University of Athens, Attikon University Hospital, Athens, Greece. Electronic address: lrallidis@gmail.com.
² Department of Internal Medicine, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, Greece.
³ 1st Department of Cardiology, Medical School, National and Kapodistrian University of Athens, Hippokration Hospital, Athens, Greece.
⁴ Cardiometabolic Center, Lipoprotein Apheresis and Lipid Disorders Clinic, Metropolitan Hospital, Athens, Greece.
⁵ 2nd Department of Cardiology, Medical School, National and Kapodistrian University of Athens, Attikon University Hospital, Athens, Greece.

No abstract available

Keywords: Familial hypercholesterolaemia; LDL-Cholesterol target; Lipid-lowering therapy; PCSK9 inhibitors; Very-high risk.

Comment on

2019 ESC/EAS guidelines for the management of dyslipidaemias: Lipid modification to reduce cardiovascular risk.
Authors/Task Force Members; ESC Committee for Practice Guidelines (CPG); ESC National Cardiac Societies. Authors/Task Force Members, et al. Atherosclerosis. 2019 Nov;290:140-205. doi: 10.1016/j.atherosclerosis.2019.08.014. Epub 2019 Aug 31. Atherosclerosis. 2019. PMID: 31591002 Review. No abstract available.