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. 2020 Aug 11;6(3):146-151.
doi: 10.2478/jccm-2020-0022. eCollection 2020 Jul.

Takotsubo Syndrome: Is this a Common Occurrence in Elderly Females after Hip Fracture?

Carlo Rostagno  1 , Gianluca Polidori  2 , Alice Ceccofiglio  2 , Alessandro Cartei  2 , Alberto Boccaccini  2 , Adriano Peris  2 , Gaia Rubbieri  2 , Roberto Civinini  1 , Massimo Innocenti  1
Affiliations

Takotsubo Syndrome: Is this a Common Occurrence in Elderly Females after Hip Fracture?

Carlo Rostagno et al. J Crit Care Med (Targu Mures). .

Abstract

Background: The prevalence of Takotsubo syndrome in hip fracture is not known.

Methods: Hip fracture patients were evaluated in a multidisciplinary unit. Patients with ECG abnormalities and increased troponin I values at the time of hospital admission were included in the study Follow-up was clinical at 30 days and by telephonic interview at one year.

Results: Between October 1st 2011 to September 30th 2016, 51 of 1506 patients had preoperative evidence of myocardial damage. Eight, all females, fulfilled the Mayo criteria for Takotsubo syndrome, six had no coronary lesions. Hip surgery was uneventful, and all eight were alive at thirty days, and seven of these were still alive after one year. Forty-three patients had myocardial infarction: mortality at thirty days and one year were 11% and 44% (p<0.0001, Student's t-test; log-rank test).

Conclusion: At least 15% of patients with hip fracture and preoperative myocardial damage had Takotsubo syndrome. They were all elderly females. Contrary to myocardial infarction, Takotsubo syndrome has a favourable long term prognosis.

Keywords: Takotsubo syndrome; hip-fracture; ischemic heart disease.

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Conflict of interest statement

Conflict of interest None to declare.

References

    1. Thiagarajah S, Fenton A, Sivardeen Z, Stanley D. The management and mortality of patients undergoing hip fracture surgery following recent acute myocardial infarction Acta Orthop. Belg. 2011;77:626–31. - PubMed
    1. Gupta BP, Huddleston JM, Kirkland LL. Clinical Presentation and Outcome of Perioperative Myocardial Infarction in Very Elderly Following Hip Fracture Surgery J Hosp Med. 2012;7:713–6. et al. - PMC - PubMed
    1. Hietala P, Strandberg M, Strandberg N. Peri-operative myocardial infarctions are common and often unrecognized in patients undergoing hip fracture surgery. J Trauma Acute Care Surg. 2013;74:1087–91. et al. - PubMed
    1. Gianni M, Dentali F, Grandi AM. Apical ballooning syndrome or Takotsubo cardiomyopathy: a systematic review. Eur Heart J. 2006;7:1523–9. et al. - PubMed
    1. Lyon AR, Bossone E, Schneider B. Current state of knowledge on Takotsubo syndrome: a Position Statement from the Taskforce on Takotsubo Syndrome of the Heart FailureAssociation of the European Society of Cardiology. Eur J Heart Fail. 2016;18:8–27. et al. - PubMed

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