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Case Reports
. 2020 Aug 1;38(4):460-463.
doi: 10.7518/hxkq.2020.04.019.

[Bisphosphonate-related osteonecrosis of the jaw caused by implant: a case report]

[Article in Chinese]
Ping-Fan Wu  1 , Yu Li  1 , Zhen-Ge Lei  1 , Lin-Lin Chen  1
Affiliations
Case Reports

[Bisphosphonate-related osteonecrosis of the jaw caused by implant: a case report]

[Article in Chinese]
Ping-Fan Wu et al. Hua Xi Kou Qiang Yi Xue Za Zhi. .

Abstract
in English, Chinese

Osteonecrosis of the jaw could occur after intake of bisphosphonate drugs, which are widely used to treat osteoporosis and bone metastasis of malignant tumors. This effect has aroused concern among dentists. In this paper, a case of bisphosphonate-related osteonecrosis caused by implant is reported, and the pathogenesis, diagnosis, prevention, and treatment of bisphosphonate drug-induced osteonecrosis are described through a literature review. The effects of bisphosphonate drug treatment on dental implants are also discussed.

随着双膦酸盐类药物在骨质疏松、恶性肿瘤骨转移等方面的广泛应用，不断有颌骨坏死发生的报道，已逐渐引起口腔医生的高度关注。本文报道1例种植体植入术后引起双膦酸盐相关性颌骨坏死的病例，并结合相关文献阐述双膦酸盐类药物性颌骨坏死的发病机制、诊断、预防及治疗方法，进一步讨论使用双膦酸盐后对种植体的影响。.

Keywords: bisphosphonate; implant; jaw; osteonecrosis.

PubMed Disclaimer

Conflict of interest statement

利益冲突声明：作者声明本文无利益冲突。

Figures

图 1
图 1. 术前口内观及CBCT
Fig 1 Intraoral view and CBCT before operation A：口内暴露的死骨及种植体（箭头）；B：全景片（箭头示种植体）；C：CBCT三维重建（箭头示种植体）；D：分离的死骨（箭头）。
图 2
图 2. 术中切除的死骨及种植体
Fig 2 Dead bone and implant removed during operation
图 3
图 3. 术后病理 苏木精-伊红 × 100
Fig 3 Postoperative pathology hematoxylin-eosin × 100
图 4
图 4. 术后1个月口内观
Fig 4 Intraoral view one month after surgery
See this image and copyright information in PMC

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References

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