Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1988 Jun;170(6):2457-61.
doi: 10.1128/jb.170.6.2457-2461.1988.

Osmotic regulation of biosynthesis of membrane-derived oligosaccharides in Escherichia coli

E P Kennedy  1 , M K Rumley
Affiliations

Osmotic regulation of biosynthesis of membrane-derived oligosaccharides in Escherichia coli

E P Kennedy et al. J Bacteriol. 1988 Jun.

Abstract

The osmotic regulation of the biosynthesis of membrane-derived oligosaccharides (MDO) in strains UB1005 and DC2 of Escherichia coli K-12 was examined; this regulation was previously reported by Clark (J. Bacteriol. 161:1049-1053, 1985) to be different from that observed by Kennedy for other strains of E. coli (Proc. Natl. Acad. Sci. USA 79:1092-1095, 1982). Osmotic regulation of the synthesis of MDO in UB1005 and DC2 is in fact indistinguishable from that previously reported for other strains of E. coli, with maximum production of MDO occurring in the medium of lowest osmolarity. The report of Clark to the contrary was apparently based on the inadequate methods for the measurement of MDO employed in that study. MDO are localized in the periplasm of wild-type E. coli cells. However, strain DC2, selected for hypersensitivity to a range of antibiotics, released most of its MDO into the medium, apparently as a result of greater outer membrane permeability.

PubMed Disclaimer

References

    1. Proc Natl Acad Sci U S A. 1973 May;70(5):1368-72 - PubMed
    1. J Bacteriol. 1973 Oct;116(1):257-62 - PubMed
    1. J Biol Chem. 1976 Jul 25;251(14):4208-13 - PubMed
    1. J Biol Chem. 1978 Jun 10;253(11):3882-7 - PubMed
    1. Science. 1986 Jan 3;231(4733):48-51 - PubMed

Publication types

MeSH terms

Substances