Igniting the spread of ferroptotic cell death

Affiliations

¹ Centre for Inflammation Research, University of Edinburgh, Queens Medical Research Institute, Edinburgh, UK.
² Centre for Inflammation Research, University of Edinburgh, Queens Medical Research Institute, Edinburgh, UK. w.wood@ed.ac.uk.

Comment

Andrew J Davidson et al. Nat Cell Biol. 2020 Sep.

. 2020 Sep;22(9):1027-1029.

doi: 10.1038/s41556-020-0570-4.

¹ Centre for Inflammation Research, University of Edinburgh, Queens Medical Research Institute, Edinburgh, UK.
² Centre for Inflammation Research, University of Edinburgh, Queens Medical Research Institute, Edinburgh, UK. w.wood@ed.ac.uk.

No abstract available

Comment on

Lipid peroxidation regulates long-range wound detection through 5-lipoxygenase in zebrafish.
Katikaneni A, Jelcic M, Gerlach GF, Ma Y, Overholtzer M, Niethammer P. Katikaneni A, et al. Nat Cell Biol. 2020 Sep;22(9):1049-1055. doi: 10.1038/s41556-020-0564-2. Epub 2020 Aug 31. Nat Cell Biol. 2020. PMID: 32868902 Free PMC article.
Ferroptosis occurs through an osmotic mechanism and propagates independently of cell rupture.
Riegman M, Sagie L, Galed C, Levin T, Steinberg N, Dixon SJ, Wiesner U, Bradbury MS, Niethammer P, Zaritsky A, Overholtzer M. Riegman M, et al. Nat Cell Biol. 2020 Sep;22(9):1042-1048. doi: 10.1038/s41556-020-0565-1. Epub 2020 Aug 31. Nat Cell Biol. 2020. PMID: 32868903 Free PMC article.

1. Galluzzi, L. et al. Cell Death Differ. 25, 486–541 (2018). - DOI
1. Green, D.R. Cell Death: Apoptosis and Other Means to an End. 2nd edn. (Cold Spring Harbor Laboratory Press, New York, 2018).
1. Degterev, A. et al. Nat. Chem. Biol. 1, 112–119 (2005). - DOI
1. Medina, C. B. et al. Nature 580, 130–135 (2020). - DOI
1. Dixon, S. J. et al. Cell 149, 1060–1072 (2012). - DOI