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. 2020 Sep-Oct;34(5):2607-2612.
doi: 10.21873/invivo.12078.

Anatomical Versus Non-anatomical Resection for Hepatocellular Carcinoma, a Propensity-matched Analysis Between Taiwanese and Japanese Patients

Affiliations

Anatomical Versus Non-anatomical Resection for Hepatocellular Carcinoma, a Propensity-matched Analysis Between Taiwanese and Japanese Patients

Shih-Wei Huang et al. In Vivo. 2020 Sep-Oct.

Abstract

Background/aim: The aim of the study was to compare the outcomes of anatomical resection (AR) versus non-anatomical resection (NAR) for Japanese and Taiwanese patients with single, resectable hepatocellular carcinoma (HCC).

Patients and methods: A propensity score matched (PSM) analysis was performed to compare the outcomes of the AR group to those of the NAR group. Tumor size <5 cm, T1 or T2 grade, without evidence of extrahepatic metastasis, invasion of portal or hepatic veins, or direct invasion of adjacent organs, were included in the study.

Results: A total of 385 cases (Taiwanese 105, Japanese 280) were analyzed. After PSM, a total of 152 cases remain (Taiwan and Japan both 76 cases). Disease-free survival (DFS) and overall survival (OS) data were not significantly different between the two groups at 5 years follow-up.

Conclusion: AR of HCC in Japanese patients has a similar 5-year DFS and OS as NAR of HCC in Taiwanese patients.

Keywords: Anatomical resection; Japan; Taiwan; disease-free survival; hepatocellular carcinoma; non-anatomical resection; overall survival; propensity score matched analysis.

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Conflict of interest statement

The Authors have no conflicts of interest to declare.

Figures

Figure 1
Figure 1. Kaplan-Meier curves of DFS (A) and OS (B) of the HCC patients with NAR from Taiwan and those with AR from Japan.

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