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. 2020 Sep-Oct;34(5):2897-2903.
doi: 10.21873/invivo.12118.

Improvement in Left Cardiac Function Following Mitral Valve Repair: Analyses Based on Cardiac Magnetic Resonance Imaging

Yoshihiro Hayata  1 , Noriyoshi Sawabata  2 , Takehisa Abe  1 , Tomoaki Hirose  1 , Keigo Yamashita  1 , Shun Hiraga  1 , Ryohei Fukuba  1 , Junichi Takemura  1 , Tomoya Nakano  3 , Yoshihiko Saito  3 , Shigeki Taniguchi  1
Affiliations

Improvement in Left Cardiac Function Following Mitral Valve Repair: Analyses Based on Cardiac Magnetic Resonance Imaging

Yoshihiro Hayata et al. In Vivo. 2020 Sep-Oct.

Abstract

Aim: This study aimed to evaluate the structural and functional changes of left-sided cardiac chambers by cardiac magnetic resonance imaging (CMRI) in patients with chronic mitral regurgitation after mitral valve repair (MVR).

Patients and methods: Among 103 patients who underwent MVR, 21 showed normal left ventricular (LV) function; their pre- and postoperative left atrial (LA) and LV functions were examined by CMRI.

Results: LV end-diastolic volume, LV end-systolic volume, and LV mass significantly were reduced postoperatively (p<0.01) and postoperative LV ejection fraction tended to decrease. LA volume parameters also significantly decreased postoperatively (p<0.01). The conduit function positively affected the LV filling volume postoperatively (p<0.01); however, no effect on the booster pump function was noted (p=0.01).

Conclusion: Restoration of LA and LV functions after a successful MVR was not associated with structural improvement in LA and LV.

Keywords: Mitral regurgitation; cardiac magnetic resonance; left atrium; left ventricle; mitral valve repair.

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Conflict of interest statement

All Authors declare no conflicts of interest associated with this study.

Figures

Figure 1
Figure 1. Boxplots showing the minimum, first quartile, median, third quartile, and maximum left ventricular end-diastolic volume index (LVEDVI) (A), left ventricular end-systolic volume index (LVESVI) (B), left ventricular ejection fraction (LVEF) (C), and left ventricular mass index (LVMI) (D) before (Pre) and after (Post) mitral valve repair.
Figure 2
Figure 2. Boxplots showing the minimum, first quartile, median, third quartile, and maximum static volumes of the left atrium (LA) before (Pre) and after (Post) mitral valve repair. A: Maximum LA volume (LAVmax). B: LA volume immediately before atrial contraction (LAVpreA). C: minimum LA volume (LAVmin). All volumes were indexed to body surface area.
Figure 3
Figure 3. Contribution of each phasic function of the left atrium (LA) to the total stroke volume of the left ventricle. No difference in the reservoir function before (Pre) and after (Post) mitral valve repair was found. Postoperative conduit function had a significantly greater contribution, whereas postoperative booster pump function had significantly less contribution to left ventricular filling than preoperatively.
See this image and copyright information in PMC

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