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. 2020 Aug 14;99(33):e21711.
doi: 10.1097/MD.0000000000021711.

Effects of spore powder of ganoderma lucidum on CaSR and apoptosis-related proteins in hippocampus tissue of epilepsy following dementia: A protocol of systematic review

Li-Hong Qin  1 , Chen Wang  2 , Xiao-Xue Jiang  3 , You Song  1 , Yao Feng  4 , Li-Wei Qin  5 , Shu-Ping Zhang  1
Affiliations

Effects of spore powder of ganoderma lucidum on CaSR and apoptosis-related proteins in hippocampus tissue of epilepsy following dementia: A protocol of systematic review

Li-Hong Qin et al. Medicine (Baltimore). .

Abstract

Background: This study will investigate the effects of Spore Powder of Ganoderma Lucidum (SPGL) on CaSR and apoptosis-related proteins (ARP) in hippocampus tissue of epilepsy following dementia.

Methods: This study will retrieve all potential studies from both electronic databases (Cochrane Library, EMBASE, MEDLINE, CINAHL, AMED, and CNKI) and other literature sources to assess the effects of SPGL on CaSR and ARP in hippocampus tissue of epilepsy following dementia. We will search all literature sources from the inception to the present. All eligible case-control studies will be included in this study. Two authors will independently carry out literature selection, data collection, and study quality evaluation. Any divergence will be resolved by another author through discussion. RevMan 5.3 software will be employed for data analysis.

Results: This study will summarize existing evidence to assess the effects of SPGL on CaSR and ARP in hippocampus tissue of epilepsy following dementia.

Conclusions: The findings of this study may provide helpful evidence of SPGL on CaSR and ARP in hippocampus tissue of epilepsy following dementia.

Systematic review registration: INPLASY202070041.

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Conflict of interest statement

The authors have no conflicts of interest to disclose.

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