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. 2020 Aug 30;17(17):6308.
doi: 10.3390/ijerph17176308.

The Burden of Cervical Cancer in Korea: A Population-Based Study

Jinhee Kim  1 , Donghwan Lee  2 , Kyung-Bok Son  1 , SeungJin Bae  1
Affiliations

The Burden of Cervical Cancer in Korea: A Population-Based Study

Jinhee Kim et al. Int J Environ Res Public Health. .

Abstract

This study used the Korean National Health Insurance (NHI) claims database from 2011 to 2017 to estimate the incidence and the incidence-based cost of cervical cancer and carcinoma in situ of cervix uteri (CIS) in Korea. The primary outcome was the direct medical cost per patient not diagnosed with cervical cancer (C53) or CIS (D06) 2 years prior to the index date in the first year after diagnosis. A regression analysis was conducted to adjust for relevant covariates. The incidence of cervical cancer tended to decrease from 2013 to 2016, while that of CIS increased. In particular, the incidence rate of CIS in women in their 20 s and 30 s increased by 56.8% and 28.4%, respectively, from 2013 to 2016. The incidence-based cost of cervical cancer and CIS was USD 13,058 and USD 2695 in 2016, respectively, which increased from 2013. Multivariate regression analysis suggested that age was the most influential variable of the cost in both patient groups, and the cost was highest in those aged over 60, i.e., the medical cost was significantly lower in younger women than their older counterparts. These findings suggest that targeting younger women in cervical cancer prevention is a reasonable option from both economic and public health perspectives.

Keywords: HPV; burden of disease; carcinoma in situ; cervical cancer; cost; incidence.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure A1
Figure A1
Incidence-based medical cost per patient with cervical cancer and CIS by year.
Figure A1
Figure A1
Incidence-based medical cost per patient with cervical cancer and CIS by year.
Figure 1
Figure 1
Study design of operational definition of new patients between 2013 and 2016.
Figure 2
Figure 2
Age-specific incidence rate and mean medical costs of cervical cancer and CIS by year. (a) The age-specific incidence rate of cervical cancer was calculated per 100,000 people. (b) The mean medical cost of cervical cancer was adjusted by the 2016 medical care component CPI and converted to US dollars. (c) The age-specific incidence rate of CIS was calculated per 100,000 people. (d) The mean medical cost of CIS was adjusted by the 2016 medical care component of CPI and converted to US dollars.
See this image and copyright information in PMC

References

    1. Ferlay J., Colombet M., Soerjomataram I., Mathers C., Parkin D.M., Piñeros M., Znaor A., Bray F. Estimating the global cancer incidence and mortality in 2018: GLOBOCAN sources and methods. Int. J. Cancer. 2018;144:1941–1953. doi: 10.1002/ijc.31937. - DOI - PubMed
    1. Annual Report of Cancer Statistics in Korea in 2016. [(accessed on 20 August 2019)]; Available online: File:///C:/Users/MDPI/AppData/Local/Temp/Annual_report_of_cancer_statist....
    1. Kitchener H., Castle P.E., Cox J.T. Chapter 7: Achievements and limitations of cervical cytology screening. Vaccine. 2006;24:S63–S70. doi: 10.1016/j.vaccine.2006.05.113. - DOI - PubMed
    1. Lee K.W., Song J.Y. Epidemiology of Cervical Cancer. J. Korean Med. Assoc. 2007;50:762. doi: 10.5124/jkma.2007.50.9.762. - DOI
    1. Braaten K.P., Laufer M.R. Human Papillomavirus (HPV), HPV-Related Disease, and the HPV Vaccine. Rev. Obstet. Gynecol. 2008;1:2–10. - PMC - PubMed

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