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. 2021 May;44(5):1065-1073.
doi: 10.1007/s40618-020-01407-1. Epub 2020 Sep 2.

Thyroid surgery during coronavirus-19 pandemic phases I, II and III: lessons learned in China, South Korea, Iran and Italy

D Zhang  1 , Y Fu  1 , L Zhou  1 , N Liang  1 , T Wang  1 , P Del Rio  2 , S Rausei  3 , L Boni  4 , D Park  5 , J Jafari  6 , S Kargar  6 , H Y Kim  5 , M L Tanda  7 , G Dionigi  8 , H Sun  9
Affiliations

Thyroid surgery during coronavirus-19 pandemic phases I, II and III: lessons learned in China, South Korea, Iran and Italy

D Zhang et al. J Endocrinol Invest. 2021 May.

Abstract

Objective: We compared demographic and clinic-pathological variables related to the number of surgeries for thyroid conditions or for cancer, morbidity, and fine needle aspiration (FNA) practices among Covid19 pandemic phases I, II, III and the same seasonal periods in 2019.

Methods: The prospective database of the Division of Thyroid Surgery, China-Japan Union Hospital of Jilin University, Changchun, China was used for this study. Covid19 emergency levels were stratified according to the World Health Organization: phase I (January 25-February 25, 2020), phase II (February 26-March 19), phase III (March 20-April 20).

Results: There were fewer outpatient FNAs and surgeries in 2020 than in 2019. There were no thyroid surgeries during phase I. There were also fewer surgeries for cancer with a significant reduction of advanced stage cancer treatments, mainly stage T1b N1a in phase II and T3bN1b in phase III. Operative times and postoperative stays were significantly shorter during the pandemic compared to our institutional baseline. In phase III, vocal cord paralysis (VCP) increased to 4.3% of our baseline numbers (P = 0.001). There were no cases of Covid19-related complications during the perioperative period. No patients required re-admission to the hospital.

Conclusion: The Covid19 outbreak reduced thyroid surgery patient volumes. The decrease of Covid19 emergency plans contributed to unexpected outcomes (reduction of early stage cancer treatment, decreased operative times and hospital stays, increased VCP rate).

Keywords: Cancer; China; Covid19; Iran; Italy; Morbidity; Recurrent laryngeal nerve palsy; SARS-CoV-2; South Korea; Surgery; Surgical practice; Thyroid; Thyroidectomy.

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Conflict of interest statement

All Authors report having no relationships that could be construed as a conflict of interest.

Figures

Fig. 1
Fig. 1
Graphs showing comparison of a the number of outpatients visits, b number of FNA and c FNA proportion of malignancy, at the Division of Thyroid Surgery of the China–Japan Union Hospital of Jilin University (Changchun, People’s Republic of China), during Covid19 emergency phases I, II, III and year 2019
See this image and copyright information in PMC

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