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Editorial
. 2021 Feb;34(1):3-5.
doi: 10.1007/s40620-020-00851-9.

Outbreak of chronic renal failure: will this be a delayed heritage of COVID-19?

Niloofar Khoshdel-Rad  1   2 , Ensieh Zahmatkesh  1   2 , Anastasia Shpichka  3   4 , Peter Timashev  5   6   7 , Massoud Vosough  8   9
Affiliations
Editorial

Outbreak of chronic renal failure: will this be a delayed heritage of COVID-19?

Niloofar Khoshdel-Rad et al. J Nephrol. 2021 Feb.
No abstract available

Keywords: Acute kidney injury; COVID-19; Chronic renal failure; Coronavirus; Renal damage; SARS-CoV-2.

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Fig. 1
Fig. 1
Kidney injuries in COVID-19 patients. The SARS-CoV-2 virus enters into the renal cells through binding to the ACE-2 receptors. SARS-CoV-2 infection contributes to acute injuries including loss of brush border, lumen dilation, disruption of mitochondria, and necrosis in tubular proximal cells. Moreover, COVID-19 is related to the detachment of perivascular pericytes, sub-endothelial space expansion, erythrocyte aggregation, and blood clot formation in the intra-renal vasculature. Incomplete recovery from AKI, continuous interstitial inflammation, the loss of the regenerative potential of renal vascular cells, and hypertension are often related to the increased risk of CRF progression and dialysis during the long-term periods after hospitalization
See this image and copyright information in PMC

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