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Review
. 2020 Aug 31;10(9):659.
doi: 10.3390/diagnostics10090659.

Postembolization Syndrome after Prostatic Artery Embolization: A Systematic Review

Petra Svarc  1 , Mikkel Taudorf  1 , Michael Bachmann Nielsen  1 , Hein Vincent Stroomberg  2 , Martin Andreas Røder  2 , Lars Lönn  1
Affiliations
Review

Postembolization Syndrome after Prostatic Artery Embolization: A Systematic Review

Petra Svarc et al. Diagnostics (Basel). .

Abstract

Postembolization syndrome (PES) is the most common side effect of vascular embolization of solid organs. The aim of this review was to determine the incidence of PES and its individual components after prostatic artery embolization (PAE). A systematic review with a pre-specified search strategy for PubMed, Embase, Web of Science and Cochrane Library was performed according to PRISMA guidelines. Studies in English regarding PAE in humans with 10 or more participants were eligible for inclusion. No restrictions on participant demographics or PAE technique were imposed. The search returned 378 references, of which 32 studies with a total of 2116 patients met the inclusion criteria. The results for overall PES frequency and individual PES components were presented as median (interquartile range, (IQR)). Overall median PES frequency was 25.5% (12.5-45.8). The two most frequent individual PES components were dysuria/urethral burning and local pain, with a median frequency of 21.7% (13.8-33.3) and 20% (5.4-29.4), respectively. Most outcome measures were characterized by a marked lack of uniformity and inconsistency in reporting across studies. Development of a uniform reporting system would help the clinicians recognize and treat PES accordingly.

Keywords: benign prostatic hyperplasia; postembolization syndrome; prostatic artery embolization.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure A1
Figure A1
Risk of bias in non-randomized studies-of interventions (ROBINS-I) assessments of non-RCTs. (a) “Traffic-light” illustration of risk of bias in individual studies. (b) Weighted bar plots depicting risk of bias judgement distributions within each domain.
Figure A1
Figure A1
Risk of bias in non-randomized studies-of interventions (ROBINS-I) assessments of non-RCTs. (a) “Traffic-light” illustration of risk of bias in individual studies. (b) Weighted bar plots depicting risk of bias judgement distributions within each domain.
Figure 1
Figure 1
PRISMA flow diagram.
Figure 2
Figure 2
Median frequency of PES and its components. Box = 25th and 75th percentiles; bars = minimum and maximum values (1.5× IQR); bold line = median; N = number of studies included; outliers represented as circles. LUTS, lower urinary tract symptoms; PES, postembolization syndrome; NOS, not otherwise specified.
Figure 3
Figure 3
RoB2 assessments of RCTs. (a) “Traffic-light” illustration of risk of bias in individual studies. (b) Weighted bar plots depicting risk of bias judgement distributions within each domain.
See this image and copyright information in PMC

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