Cohort Profile: IAVI's HIV epidemiology and early infection cohort studies in Africa to support vaccine discovery

Matt A Price^{1

2}, William Kilembe^{3

4}, Eugene Ruzagira⁵, Etienne Karita^{3

4}, Mubiana Inambao^{3

4}, Eduard J Sanders^{6

7}, Omu Anzala⁸, Susan Allen^{3

4

9}, Vinodh A Edward^{10

11

12

13}, Pontiano Kaleebu⁵, Patricia E Fast^{1

14}, Wasima Rida¹⁵, Anatoli Kamali¹, Eric Hunter^{3

4

9}, Jianming Tang¹⁶, Shabir Lakhi^{3

4}, Gaudensia Mutua⁸, Linda Gail Bekker¹⁷, Ggayi Abu-Baker⁵, Amanda Tichacek^{3

4

18}, Paramesh Chetty¹, Mary H Latka¹⁰, Pholo Maenetje¹⁰, Heeran Makkan¹⁰, Jonathan Hare¹⁹, Freddie Kibengo⁵, Fran Priddy¹, Elise Landais^{1

20

21}, Kundai Chinyenze¹, Jill Gilmour¹⁹

Affiliations

¹ IAVI, New York, USA & Nairobi, Kenya.
² Department of Epidemiology and Biostatistics, University of California at San Francisco, San Francisco, CA, USA.
³ Rwanda Zambia Emory HIV Research Group, Lusaka & Ndola, Zambia; Kigali, Rwanda.
⁴ Emory University, Atlanta, GA, USA.
⁵ Medical Research Council, Uganda Virus Research Institute, and London School of Hygiene and Tropical Medicine Uganda Research Unit (MULS), Entebbe & Masaka, Uganda.
⁶ Kenyan Medical Research Institute-Wellcome Trust, Kilifi, Kenya.
⁷ Nuffield Department of Clinical Medicine, Centre for Clinical Vaccinology and Tropical Medicine, University of Oxford, Headington, UK.
⁸ KAVI-Institute of Clinical Research, Nairobi, Kenya.
⁹ Department of Pathology and Laboratory Medicine, Emory University, Atlanta, GA, USA.
¹⁰ The Aurum Institute, Johannesburg and Rustenburg, South Africa.
¹¹ School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
¹² Advancing Care and Treatment for TB/HIV, A Collaborating Centre of the South African Medical Research Council, Cape Town, South Africa.
¹³ Department of Environmental Health Sciences, Yale School of Public Health, New Haven, CT, USA.
¹⁴ Pediatric Infectious Diseases, School of Medicine, Stanford University, Palo Alto, CA, USA.
¹⁵ Biostatistics Consultant, Arlington, VA, USA.
¹⁶ Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
¹⁷ Desmond Tutu HIV Centre, University of Cape Town, Cape Town, South Africa.
¹⁸ Department of Epidemiology, Emory University, Atlanta, GA, USA.
¹⁹ IAVI Human Immunology Laboratory, Imperial College, London, UK.
²⁰ IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA.
²¹ Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.

PMID: 32879950
PMCID: PMC7938500
DOI: 10.1093/ije/dyaa100

Cohort Profile: IAVI's HIV epidemiology and early infection cohort studies in Africa to support vaccine discovery

Matt A Price et al. Int J Epidemiol. 2021.

. 2021 Mar 3;50(1):29-30.

doi: 10.1093/ije/dyaa100.

Authors

Affiliations

¹ IAVI, New York, USA & Nairobi, Kenya.
² Department of Epidemiology and Biostatistics, University of California at San Francisco, San Francisco, CA, USA.
³ Rwanda Zambia Emory HIV Research Group, Lusaka & Ndola, Zambia; Kigali, Rwanda.
⁴ Emory University, Atlanta, GA, USA.
⁵ Medical Research Council, Uganda Virus Research Institute, and London School of Hygiene and Tropical Medicine Uganda Research Unit (MULS), Entebbe & Masaka, Uganda.
⁶ Kenyan Medical Research Institute-Wellcome Trust, Kilifi, Kenya.
⁷ Nuffield Department of Clinical Medicine, Centre for Clinical Vaccinology and Tropical Medicine, University of Oxford, Headington, UK.
⁸ KAVI-Institute of Clinical Research, Nairobi, Kenya.
⁹ Department of Pathology and Laboratory Medicine, Emory University, Atlanta, GA, USA.
¹⁰ The Aurum Institute, Johannesburg and Rustenburg, South Africa.
¹¹ School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
¹² Advancing Care and Treatment for TB/HIV, A Collaborating Centre of the South African Medical Research Council, Cape Town, South Africa.
¹³ Department of Environmental Health Sciences, Yale School of Public Health, New Haven, CT, USA.
¹⁴ Pediatric Infectious Diseases, School of Medicine, Stanford University, Palo Alto, CA, USA.
¹⁵ Biostatistics Consultant, Arlington, VA, USA.
¹⁶ Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
¹⁷ Desmond Tutu HIV Centre, University of Cape Town, Cape Town, South Africa.
¹⁸ Department of Epidemiology, Emory University, Atlanta, GA, USA.
¹⁹ IAVI Human Immunology Laboratory, Imperial College, London, UK.
²⁰ IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA.
²¹ Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.

PMID: 32879950
PMCID: PMC7938500
DOI: 10.1093/ije/dyaa100

No abstract available

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Figures

**Figure 1.**
Participating clinical research centres.

See this image and copyright information in PMC

References

1. Njai HF, Gombe B, Khamis T. et al. Setting up a standardized peripheral blood mononuclear cells processing laboratory to support multi-center HIV/AIDS vaccine and intervention trials. Lab Med 2011;42:711–18.
1. Ruzagira E, Wandiembe S, Abaasa A. et al. Prevalence and incidence of HIV in a rural community-based HIV vaccine preparedness cohort in Masaka, Uganda. PLoS One 2011;6:e20684. - PMC - PubMed
1. Ruzagira E, Wandiembe S, Abaasa A. et al. HIV incidence and risk factors for acquisition in HIV discordant couples in Masaka, Uganda: an HIV vaccine preparedness study. PLoS One 2011;6:e24037. - PMC - PubMed
1. Kamali A, Price MA, Lakhi S. et al. Creating an African HIV clinical research and prevention trials network: HIV prevalence, incidence and transmission. PLoS One 2015;10:e0116100. - PMC - PubMed
1. Fideli US, Allen SA, Musonda R. et al. Virologic and immunologic determinants of heterosexual transmission of human immunodeficiency virus type 1 in Africa. AIDS Res Hum Retroviruses 2001;17:901–10. - PMC - PubMed

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Cohort Profile: IAVI's HIV epidemiology and early infection cohort studies in Africa to support vaccine discovery

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Cohort Profile: IAVI's HIV epidemiology and early infection cohort studies in Africa to support vaccine discovery

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