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. 2021 Jun;268(6):2031-2034.
doi: 10.1007/s00415-020-10185-y. Epub 2020 Sep 3.

Parainfectious encephalitis in COVID-19: "The Claustrum Sign"

Frédéric Zuhorn  1 , Hassan Omaimen  2 , Bertram Ruprecht  3 , Christoph Stellbrink  4 , Michael Rauch  5 , Andreas Rogalewski  5 , Randolf Klingebiel #  2 , Wolf-Rüdiger Schäbitz #  5
Affiliations

Parainfectious encephalitis in COVID-19: "The Claustrum Sign"

Frédéric Zuhorn et al. J Neurol. 2021 Jun.
No abstract available

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Conflict of interest statement

The authors declare that they have no conflict of interest.

Figures

Fig. 1
Fig. 1
a-f MR scans 2 weeks (a–c) and 4 months (d–e) post symptom onset as well as CSF cytology (f): On axial FLAIR (a), Diffusion-weighted images (b) and the corresponding ADC map (c), bilateral signal alterations within the external capsule/claustrum regions are depicted (arrows), indicative of reduced diffusion. On follow-up imaging (d–e), the FLAIR-hyperintensities persist (d) whereas tissue diffusion has normalized (e). CSF-cytology (f) showed a slightly elevated cell count (9/µl) with a lymphocytic predominance (88% lymphocytes, 12% monocytes). A meaningful plasmacytic transformation was not observed, the monocytes being only slightly activated
See this image and copyright information in PMC

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