ISTH DIC subcommittee communication on anticoagulation in COVID-19
- PMID: 32881336
- PMCID: PMC7404846
- DOI: 10.1111/jth.15004
ISTH DIC subcommittee communication on anticoagulation in COVID-19
Abstract
Hypercoagulability is an increasingly recognized complication of SARS-CoV-2 infection. As such, anticoagulation has become part and parcel of comprehensive COVID-19 management. However, several uncertainties exist in this area, including the appropriate type and dose of heparin. In addition, special patient populations, including those with high body mass index and renal impairment, require special consideration. Although the current evidence is still insufficient, we provide a pragmatic approach to anticoagulation in COVID-19, but stress the need for further trials in this area.
Keywords: Covid‐19; D‐dimer; anticoagulant; coagulopathy; prothrombin time.
© 2020 International Society on Thrombosis and Haemostasis.
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- Hirsh J., Warkentin T.E., Shaughnessy S.G., et al. Heparin and low‐molecular weight heparin: mechanism of action, pharmacokinetics, dosing, monitoring, efficacy and safety. Chest. 2001;119(1Suppl):64S–95S. - PubMed
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