Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2020 Sep 1;11(9):1024.
doi: 10.3390/genes11091024.

Special Issue: "Genomics and Models of Nerve Sheath Tumors"

Angela C Hirbe  1 , Rebecca D Dodd  2 , Christine A Pratilas  3
Affiliations
Editorial

Special Issue: "Genomics and Models of Nerve Sheath Tumors"

Angela C Hirbe et al. Genes (Basel). .

Abstract

Nerve sheath tumors arising in the context of neurofibromatosis type 1 (NF1) include benign tumors such as cutaneous, diffuse and plexiform neurofibromas; atypical neurofibromas or atypical neurofibromatosis neoplasms of uncertain biological potential (ANNUBP); and the aggressive soft tissue sarcoma, the malignant peripheral nerve sheath tumor (MPNST) [...].

Keywords: NF1; genomics; mouse models; nerve sheath tumors.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

References

    1. Staedtke V., Gray-Bethke T., Riggins G.J., Bai R.Y. Preventative Effect of Mebendazole against Malignancies in Neurofibromatosis 1. Genes. 2020;11:762. doi: 10.3390/genes11070762. - DOI - PMC - PubMed
    1. Cichowski K., Shih T.S., Schmitt E., Santiago S., Reilly K., McLaughlin M.E., Bronson R.T., Jacks T. Mouse models of tumor development in neurofibromatosis type 1. Science. 1999;286:2172–2176. doi: 10.1126/science.286.5447.2172. - DOI - PubMed
    1. Vogel K.S., Klesse L.J., Velasco-Miguel S., Meyers K., Rushing E.J., Parada L.F. Mouse tumor model for neurofibromatosis type 1. Science. 1999;286:2176–2179. doi: 10.1126/science.286.5447.2176. - DOI - PMC - PubMed
    1. Scherer A., Stephens V.R., McGivney G.R., Gutierrez W.R., Laverty E.A., Knepper-Adrian V., Dodd R.D. Distinct Tumor Microenvironments Are a Defining Feature of Strain-Specific CRISPR/Cas9-Induced MPNSTs. Genes. 2020;11:583. doi: 10.3390/genes11050583. - DOI - PMC - PubMed
    1. Moon C.I., Tompkins W., Wang Y., Godec A., Zhang X., Pipkorn P., Miller C.A., Dehner C., Dahiya S., Hirbe A.C. Unmasking Intra-tumoral Heterogeneity and Clonal Evolution in NF1-MPNST. Genes. 2020;11:499. doi: 10.3390/genes11050499. - DOI - PMC - PubMed

Publication types