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Editorial
. 2020 Sep 1;9(9):2009.
doi: 10.3390/cells9092009.

Trafficking Unconventionally via UPS

Bor Luen Tang  1
Affiliations
Editorial

Trafficking Unconventionally via UPS

Bor Luen Tang. Cells. .

Abstract

Conventional protein secretion in eukaryotic cells occurs via vesicular trafficking of proteins that are first targeted to the endoplasmic reticulum (ER), through the Golgi apparatus, and subsequently routed to the plasma membrane (PM), where membrane proteins take up residence while luminal proteins are released extracellularly [...].

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Conflict of interest statement

The author declares no conflict of interest.

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References

    1. Nickel W., Rabouille C. Mechanisms of regulated unconventional protein secretion. Nat. Rev. Mol. Cell Biol. 2009;10:148–155. doi: 10.1038/nrm2617. - DOI - PubMed
    1. Ng F., Tang B.L. Unconventional Protein Secretion in Animal Cells. Methods Mol. Biol. 2016;1459:31–46. - PubMed
    1. Nickel W., Rabouille C. Unconventional protein secretion: Diversity and consensus. Semin. Cell Dev. Biol. 2018;83:1–2. doi: 10.1016/j.semcdb.2018.03.007. - DOI - PubMed
    1. Steringer J.P., Nickel W. A direct gateway into the extracellular space: Unconventional secretion of FGF2 through self-sustained plasma membrane pores. Semin. Cell Dev. Biol. 2018;83:3–7. doi: 10.1016/j.semcdb.2018.02.010. - DOI - PubMed
    1. New J., Thomas S.M. Autophagy-dependent secretion: Mechanism, factors secreted, and disease implications. Autophagy. 2019;15:1682–1693. doi: 10.1080/15548627.2019.1596479. - DOI - PMC - PubMed

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