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Review
. 2020 Sep 1;9(9):720.
doi: 10.3390/pathogens9090720.

Abalone Viral Ganglioneuritis

Serge Corbeil  1
Affiliations
Review

Abalone Viral Ganglioneuritis

Serge Corbeil. Pathogens. .

Abstract

Abalone viral ganglioneuritis (AVG), caused by Haliotid herpesvirus-1 (HaHV-1; previously called abalone herpesvirus), is a disease that has been responsible for extensive mortalities in wild and farmed abalone and has caused significant economic losses in Asia and Australia since outbreaks occurred in the early 2000s. Researchers from Taiwan, China, and Australia have conducted numerous studies encompassing HaHV-1 genome sequencing, development of molecular diagnostic tests, and evaluation of the susceptibility of various abalone species to AVG as well as studies of gene expression in abalone upon virus infection. This review presents a timeline of the most significant research findings on AVG and HaHV-1 as well as potential future research avenues to further understand this disease in order to develop better management strategies.

Keywords: AVG; AbHV; HaHV-1; Haliotid herpesvirus-1; Haliotis spp.; abalone; abalone herpesvirus; abalone viral ganglioneuritis.

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Conflict of interest statement

The author declares no conflict of interest.

Figures

Figure 1
Figure 1
Range of abalone viral ganglioneuritis spread in 2010 Victoria, Australia (highlighted in orange).
Figure 2
Figure 2
Electron micrograph of abalone pleuropedal ganglion cell infected with the Victorian HaHV-1 isolate. Black arrows = mature capsids, white arrow = immature capsids, N = nucleus, C = cytoplasm, E = extracellular space. Micrograph provided by Alex Hyatt and Sandy Cramery, CSIRO.
Figure 3
Figure 3
(A) Section of an abalone nerve cord and ganglion with abalone viral ganglioneuritis induced lesions. There is disruption to the normal morphology of the nerve, as seen by a marked hemocyte infiltrate (*), edema (arrow), and neuronal necrosis (arrowhead/black triangle) (hematoxylin and eosin staining). Magnification 10×. Scale bar 100 µm. (B) Normal ganglion. Magnification 20×. Scale bar 50 µm.
See this image and copyright information in PMC

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